Keyword search (3,619 papers available)


Gold Nano-Island Platforms for Localized Surface Plasmon Resonance Sensing: A Short Review.

Author(s): Badilescu S, Raju D, Bathini S, Packirisamy M

Nano-islands are entities (droplets or other shapes) that are formed by spontaneous dewetting (agglomeration, in the early literature) of thin and very thin metallic (especially gold) films on a substrate, done by post-deposition heating or by using other s...

Article GUID: 33066088

Dissociable mesolimbic dopamine circuits control responding triggered by alcohol-predictive discrete cues and contexts.

Author(s): Valyear MD, Glovaci I, Zaari A, Lahlou S, Trujillo-Pisanty I, Andrew Chapman C, Chaudhri N

Nat Commun. 2020 Jul 28;11(1):3764 Authors: Valyear MD, Glovaci I, Zaari A, Lahlou S, Trujillo-Pisanty I, Andrew Chapman C, Chaudhri N

Article GUID: 32724058

Inactograms and objective sleep measures as means to capture subjective sleep problems in patients with a bipolar disorder.

Author(s): Lavin-Gonzalez P, Bourguignon C, Crescenzi O, Beaulieu S, Storch KF, Linnaranta O

Bipolar Disord. 2020 Mar 30;: Authors: Lavin-Gonzalez P, Bourguignon C, Crescenzi O, Beaulieu S, Storch KF, Linnaranta O

Article GUID: 32232937

Correction to: Differential disruption of conditioned ejaculatory preference in the male rat based on different sensory modalities by micro-infusions of naloxone to the medial preoptic area or ventral tegmental area.

Author(s): Quintana GR, Birrel M, Marceau S, Kalantari N, Bowden J, Bachoura Y, Borduas E, Lemay V, Payne JW, Cionnaith CM, Pfaus JG

Psychopharmacology (Berl). 2020 Jan 09;: Authors: Quintana GR, Birrel M, Marceau S, Kalantari N, Bowden J, Bachoura Y, Borduas E, Lemay V, Payne JW, Cionnaith CM, Pfaus JG

Article GUID: 31919562

Lab-On-A-Chip for the Development of Pro-/Anti-Angiogenic Nanomedicines to Treat Brain Diseases.

Author(s): Subramaniyan Parimalam S, Badilescu S, Sonenberg N, Bhat R, Packirisamy M

Int J Mol Sci. 2019 Dec 05;20(24): Authors: Subramaniyan Parimalam S, Badilescu S, Sonenberg N, Bhat R, Packirisamy M

Article GUID: 31817343

Nano-Bio Interactions of Extracellular Vesicles with Gold Nanoislands for Early Cancer Diagnosis.

Author(s): Bathini S, Raju D, Badilescu S, Kumar A, Ouellette RJ, Ghosh A, Packirisamy M

Res (Wash D C). 2018;2018:3917986 Authors: Bathini S, Raju D, Badilescu S, Kumar A, Ouellette RJ, Ghosh A, Packirisamy M

Article GUID: 31549028

Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer's disease.

Author(s): Hadoux X, Hui F, Lim JKH, Masters CL, Pébay A, Chevalier S, Ha J, Loi S, Fowler CJ, Rowe C, Villemagne VL, Taylor EN, Fluke C, Soucy JP, Les...

Nat Commun. 2019 Sep 17;10(1):4227 Authors: Hadoux X, Hui F, Lim JKH, Masters CL, Pébay A, Chevalier S, Ha J, Loi S, Fowler CJ, Rowe C, Villemagne VL, Taylor EN, Fluke C, Soucy JP, Lesage F, ...

Article GUID: 31530809

The NSERC Canadian Lake Pulse Network: A national assessment of lake health providing science for water management in a changing climate.

Author(s): Huot Y, Brown CA, Potvin G, Antoniades D, Baulch HM, Beisner BE, Bélanger S, Brazeau S, Cabana H, Cardille JA, Del Giorgio PA, Gregory-Eaves...

Sci Total Environ. 2019 Aug 04;695:133668 Authors: Huot Y, Brown CA, Potvin G, Antoniades D, Baulch HM, Beisner BE, Bélanger S, Brazeau S, Cabana H, Cardille JA, Del Giorgio PA, Gregory-Eaves...

Article GUID: 31419692

Differential disruption of conditioned ejaculatory preference in the male rat based on different sensory modalities by micro-infusions of naloxone to the medial preoptic area or ventral tegmental area.

Author(s): Quintana GR, Birrel M, Marceau S, Kalantari N, Bowden J, Bachoura Y, Borduas E, Lemay V, Payne JW, Cionnaith CM, Pfaus JG

Psychopharmacology (Berl). 2019 Jul 29;: Authors: Quintana GR, Birrel M, Marceau S, Kalantari N, Bowden J, Bachoura Y, Borduas E, Lemay V, Payne JW, Cionnaith CM, Pfaus JG

Article GUID: 31359118

The time-varying effect of radiotherapy after breast-conserving surgery for DCIS.

Author(s): Rakovitch E, Sutradhar R, Hallett M, Thompson AM, Gu S, Dumeaux V, Whelan TJ, Paszat L

Breast Cancer Res Treat. 2019 Jul 31;: Authors: Rakovitch E, Sutradhar R, Hallett M, Thompson AM, Gu S, Dumeaux V, Whelan TJ, Paszat L

Article GUID: 31368035

TRAMM/TrappC12 plays a role in chromosome congression, kinetochore stability, and CENP-E recruitment.

Author(s): Milev MP, Hasaj B, Saint-Dic D, Snounou S, Zhao Q, Sacher M

J Cell Biol. 2015 Apr 27;209(2):221-34 Authors: Milev MP, Hasaj B, Saint-Dic D, Snounou S, Zhao Q, Sacher M

Article GUID: 25918224

A molecular phylogeny of thermophilic fungi.

Author(s): Morgenstern I, Powlowski J, Ishmael N, Darmond C, Marqueteau S, Moisan MC, Quenneville G, Tsang A

Fungal Biol. 2012 Apr;116(4):489-502 Authors: Morgenstern I, Powlowski J, Ishmael N, Darmond C, Marqueteau S, Moisan MC, Quenneville G, Tsang A

Article GUID: 22483047

Transcriptome and exoproteome analysis of utilization of plant-derived biomass by Myceliophthora thermophila.

Author(s): Kolbusz MA, Di Falco M, Ishmael N, Marqueteau S, Moisan MC, Baptista CDS, Powlowski J, Tsang A

Fungal Genet Biol. 2014 Nov;72:10-20 Authors: Kolbusz MA, Di Falco M, Ishmael N, Marqueteau S, Moisan MC, Baptista CDS, Powlowski J, Tsang A

Article GUID: 24881579

Phylogeny reconstruction and hybrid analysis of populus (Salicaceae) based on nucleotide sequences of multiple single-copy nuclear genes and plastid fragments.

Author(s): Wang Z, Du S, Dayanandan S, Wang D, Zeng Y, Zhang J

PLoS One. 2014;9(8):e103645 Authors: Wang Z, Du S, Dayanandan S, Wang D, Zeng Y, Zhang J

Article GUID: 25116432

mycoCLAP, the database for characterized lignocellulose-active proteins of fungal origin: resource and text mining curation support.

Author(s): Strasser K, McDonnell E, Nyaga C, Wu M, Wu S, Almeida H, Meurs MJ, Kosseim L, Powlowski J, Butler G, Tsang A

Database (Oxford). 2015;2015: Authors: Strasser K, McDonnell E, Nyaga C, Wu M, Wu S, Almeida H, Meurs MJ, Kosseim L, Powlowski J, Butler G, Tsang A

Article GUID: 25754864

Fungal Genomic DNA Extraction Methods for Rapid Genotyping and Genome Sequencing.

Author(s): Bellemare A, John T, Marqueteau S

Methods Mol Biol. 2018;1775:11-20 Authors: Bellemare A, John T, Marqueteau S

Article GUID: 29876805

Tuning of Morphology and Stability of Gold Nanostars Through pH Adjustment.

Author(s): Kumar R, Badilescu S, Packirisamy M

J Nanosci Nanotechnol. 2019 Aug 01;19(8):4617-4622 Authors: Kumar R, Badilescu S, Packirisamy M

Article GUID: 30913757

Phylogenetic Analysis of Protein Family.

Author(s): Song L, Wu S, Tsang A

Phylogenetic Analysis of Protein Family.

Methods Mol Biol. 2018;1775:267-275

Authors: Song L, Wu S, Tsang A

Abstract
With the number of sequenced genomes increasing rapidly, it is impractical to perform functional and stru...

Article GUID: 29876824

The effect of hydrogen nanobubbles on the morphology of gold-gelatin bionanocomposite films and their optical properties.

Author(s): Alsawafta M, Badilescu S, Truong VV, Packirisamy M

Nanotechnology. 2012 Feb 17;23(6):065305 Authors: Alsawafta M, Badilescu S, Truong VV, Packirisamy M

Article GUID: 22248640

Laser-induced micropore formation and modification of cartilage structure in osteoarthritis healing.

Author(s): Sobol E, Baum O, Shekhter A, Wachsmann-Hogiu S, Shnirelman A, Alexandrovskaya Y, Sadovskyy I, Vinokur V

J Biomed Opt. 2017 09 01;22(9):91515 Authors: Sobol E, Baum O, Shekhter A, Wachsmann-Hogiu S, Shnirelman A, Alexandrovskaya Y, Sadovskyy I, Vinokur V

Article GUID: 28564689

Self-concept research with school-aged youth with intellectual disabilities: A systematic review.

Author(s): Maïano C, Coutu S, Morin AJS, Tracey D, Lepage G, Moullec G

J Appl Res Intellect Disabil. 2019 Mar;32(2):238-255 Authors: Maïano C, Coutu S, Morin AJS, Tracey D, Lepage G, Moullec G

Article GUID: 30515961

Modeling Relapse to Pavlovian Alcohol-Seeking in Rats Using Reinstatement and Spontaneous Recovery Paradigms.

Author(s): LeCocq MR, Lahlou S, Chahine M, Padillo LN, Chaudhri N

Alcohol Clin Exp Res. 2018 Sep;42(9):1795-1806 Authors: LeCocq MR, Lahlou S, Chahine M, Padillo LN, Chaudhri N

Article GUID: 29969151

Relationships between lower body strength and the energy cost of treadmill walking in a cohort of healthy older adults: a cross-sectional analysis.

Author(s): Berryman N, Bherer L, Nadeau S, Lauzière S, Lehr L, Bobeuf F, Kergoat MJ, Vu TT, Bosquet L

Eur J Appl Physiol. 2017 Jan;117(1):53-59 Authors: Berryman N, Bherer L, Nadeau S, Lauzière S, Lehr L, Bobeuf F, Kergoat MJ, Vu TT, Bosquet L

Article GUID: 27815704


Title:Nano-Bio Interactions of Extracellular Vesicles with Gold Nanoislands for Early Cancer Diagnosis.
Authors:Bathini SRaju DBadilescu SKumar AOuellette RJGhosh APackirisamy M
Link:https://www.ncbi.nlm.nih.gov/pubmed/31549028?dopt=Abstract
DOI:10.1155/2018/3917986
Category:Res (Wash D C)
PMID:31549028
Dept Affiliation: ENCS
1 Optical Bio-Microsystems Laboratory, Department of Mechanical Industrial and Aerospace Engineering, Concordia University, Montreal, Canada.
2 Atlantic Cancer Research Institute, Moncton, New Brunswick, Canada.

Description:

Nano-Bio Interactions of Extracellular Vesicles with Gold Nanoislands for Early Cancer Diagnosis.

Res (Wash D C). 2018;2018:3917986

Authors: Bathini S, Raju D, Badilescu S, Kumar A, Ouellette RJ, Ghosh A, Packirisamy M

Abstract

Extracellular vesicles or exosomes are membrane encapsulated biological nanometric particles secreted virtually by all types of cells throughout the animal kingdom. They carry a cargo of active molecules to proximal and distal cells of the body as mechanism of physiological communication, to maintain natural homeostasis as well as pathological responses. Exosomes carry a tremendous potential for liquid biopsy and therapeutic applications. Thus, there is a global demand for simple and robust exosome isolation methods amenable to point-of-care diagnosis and quality control of therapeutic exosome manufacturing. This can be achieved by molecular profiling of the exosomes for use with specific sets of molecular-markers for diagnosis and quality control. Liquid biopsy is undoubtedly the most promising diagnosis process to advance "personalized medicine." Currently, liquid biopsy is based on circulating cancer cells, cell free-DNA, or exosomes. Exosomes potentially provide promise for early-stage diagnostic possibility; in order to facilitate superior diagnosis and isolation of exosomes, a novel platform is developed to detect and capture them, based on localized surface plasmon resonance (LSPR) of gold nanoislands, through strong affinity between exosomes and peptide called Venceremin or Vn96. Physical modeling, based on the characteristics of the gold nanoislands and the bioentities involved in the sensing, is also developed to determine the detection capability of the platform, which is optimized experimentally at each stage. Preliminary results and modeling present a relationship between the plasmonic shift and the concentration of exosomes and, essentially, indicate possibilities for label-free early diagnosis.

PMID: 31549028 [PubMed]