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Environmental Multimedia Modeling System (EMMS) for Health Risk Assessment: Key Influencing Factors and Uncertainties Researches.

Author(s): Yuan J, Chen Z, Ding S, Zhang Q, Jia Y

In this paper, a former developed Environmental Multimedia Modeling System (EMMS) combining with risk assessment Monte Carlo Method (MCM) was further used for exploring the interaction between groundwater and surface water. When using this EMMS-MCM simulati...

Article GUID: 33410257
Transcriptomic analysis suggests the inhibition of DNA damage repair in green alga Raphidocelis subcapitata exposed to roxithromycin.

Author(s): Guo J, Bai Y, Chen Z, Mo J, Li Q, Sun H, Zhang Q

Ecotoxicol Environ Saf. 2020 Jun 03;201:110737 Authors: Guo J, Bai Y, Chen Z, Mo J, Li Q, Sun H, Zhang Q

Article GUID: 32505758
Antagonistic interactions between two MAP kinase cascades in plant development and immune signaling.

Author(s): Sun T, Nitta Y, Zhang Q, Wu D, Tian H, Lee JS, Zhang Y

EMBO Rep. 2018 07;19(7): Authors: Sun T, Nitta Y, Zhang Q, Wu D, Tian H, Lee JS, Zhang Y

Article GUID: 29789386
Title:Antagonistic interactions between two MAP kinase cascades in plant development and immune signaling.
Authors:Sun T,  Nitta Y,  Zhang Q,  Wu D,  Tian H,  Lee JS,  Zhang Y
Link:https://www.ncbi.nlm.nih.gov/pubmed/29789386?dopt=Abstract
DOI:10.15252/embr.201745324
Category:EMBO Rep
PMID:29789386
Dept Affiliation: BIOLOGY
1 Department of Botany, University of British Columbia, Vancouver, BC, Canada.
2 Department of Biology, Concordia University, Montreal, QC, Canada.
3 Department of Botany, University of British Columbia, Vancouver, BC, Canada yuelin.zhang@ubc.ca.

Description:

Antagonistic interactions between two MAP kinase cascades in plant development and immune signaling.

EMBO Rep. 2018 07;19(7):

Authors: Sun T, Nitta Y, Zhang Q, Wu D, Tian H, Lee JS, Zhang Y

Abstract

Mitogen-activated protein kinase (MAPK) signaling plays important roles in diverse biological processes. In Arabidopsis, MPK3/MPK6, MKK4/MKK5, and the MAPKKK YODA (YDA) form a MAPK pathway that negatively regulates stomatal development. Brassinosteroid (BR) stimulates this pathway to inhibit stomata production. In addition, MPK3/MPK6 and MKK4/MKK5 also serve as critical signaling components in plant immunity. Here, we report that MAPKKK3/MAPKKK5 form a kinase cascade with MKK4/MKK5 and MPK3/MPK6 to transduce defense signals downstream of multiple plant receptor kinases. Loss of MAPKKK3/MAPKKK5 leads to reduced activation of MPK3/MPK6 in response to different pathogen-associated molecular patterns (PAMPs) and increased susceptibility to pathogens. Surprisingly, developmental defects caused by silencing of YDA are suppressed in the mapkkk3 mapkkk5 double mutant. On the other hand, loss of YDA or blocking BR signaling leads to increased PAMP-induced activation of MPK3/MPK6. These results reveal antagonistic interactions between a developmental MAPK pathway and an immune signaling MAPK pathway.

PMID: 29789386 [PubMed - indexed for MEDLINE]