Keyword search (3,448 papers available)


Large-scale mGluR5 network abnormalities linked to epilepsy duration in focal cortical dysplasia.

Author(s): DuBois JM, Mathotaarachchi S, Rousset OG, Sziklas V, Sepulcre J, Guiot MC, Hall JA, Massarweh G, Soucy JP, Rosa-Neto P, Kobayashi E...

To determine the extent of metabotropic glutamate receptor type 5 (mGluR5) network abnormalities associated with focal cortical dysplasia (FCD), we performed graph theoretical analysis of [11C]ABP6...

Article GUID: 33401137
Neural correlates of resilience to the effects of hippocampal atrophy on memory.

Author(s): Belleville S, Mellah S, Cloutier S, Dang-Vu TT, Duchesne S, Maltezos S, Phillips N, Hudon C, CIMA-Q group...

INTRODUCTION: Cognitive reserve can be defined as a property of the brain that enables an individual to sustain cognitive performance in spite of age-related neural changes. This study uses brain i...

Article GUID: 33360019
Performance monitoring in lung cancer patients pre- and post-chemotherapy using fine-grained electrophysiological measures

Author(s): Simó M; Gurtubay-Antolin A; Vaquero L; Bruna J; Rodríguez-Fornells A;

No previous event-related potentials (ERPs) study has explored the error-related negativity (ERN) - an ERP component indexing performance monitoring - associated to cancer and chemotherapy-induced cognitive impairment in a lung cancer population. The aim of...

Article GUID: 29387526
Disruption, emergence and lateralization of brain network hubs in mesial temporal lobe epilepsy.

Author(s): Lee K, Khoo HM, Lina JM, Dubeau F, Gotman J, Grova C

Neuroimage Clin. 2018;20:71-84 Authors: Lee K, Khoo HM, Lina JM, Dubeau F, Gotman J, Grova C

Article GUID: 30094158
Pre-treatment EEG signal variability is associated with treatment success in depression.

Author(s): Jaworska N, Wang H, Smith DM, Blier P, Knott V, Protzner AB

Neuroimage Clin. 2018;17:368-377 Authors: Jaworska N, Wang H, Smith DM, Blier P, Knott V, Protzner AB

Article GUID: 29159049
Title:Neural correlates of resilience to the effects of hippocampal atrophy on memory.
Authors:Belleville S,  Mellah S,  Cloutier S,  Dang-Vu TT,  Duchesne S,  Maltezos S,  Phillips N,  Hudon C,  CIMA-Q group
Link:https://www.ncbi.nlm.nih.gov/pubmed/33360019
DOI:10.1016/j.nicl.2020.102526
Category:Neuroimage Clin
PMID:33360019
Dept Affiliation: HKAP
1 Research Center, Institut Universitaire de Gériatrie de Montréal. 4565 Queen Mary Rd, Montreal, QC H3W 1W5, Canada; Department of Psychology, Université de Montréal, Pavillon Marie-Victorin, 90 Vincent d'Indy, Montreal, QC H2V 2S9, Canada. Electronic address: sylvie.bellevillle@umontreal.ca.
2 Research Center, Institut Universitaire de Gériatrie de Montréal. 4565 Queen Mary Rd, Montreal, QC H3W 1W5, Canada. Electronic address: samira.mellah@criugm.qc.ca.
3 Research Center, Institut Universitaire de Gériatrie de Montréal. 4565 Queen Mary Rd, Montreal, QC H3W 1W5, Canada; Department of Psychology, Université de Montréal, Pavillon Marie-Victorin, 90 Vincent d'Indy, Montreal, QC H2V 2S9, Canada.
4 Research Center, Institut Universitaire de Gériatrie de Montréal. 4565 Queen Mary Rd, Montreal, QC H3W 1W5, Canada; Department of Health, Kinesiology and Applied Physiology, Concordia University, 7141 Sherbrooke Street West, Montreal, QC H4B 1R6, Canada. Electronic address: TT.DangVu@concordia.ca.
5 Department of Radiology, Université Laval, and CERVO Brain Research Center, Institut Universitaire en santé mentale de Québec, 2601 Chemin de la Canardière, Quebec City, QC G1J 2G3, Canada. Electronic address: simon.duchesne@fmed.ulaval.ca.
6 Research Center, Institut Universitaire de Gériatrie de Montréal. 4565 Queen Mary Rd, Montreal, QC H3W 1W5, Canada; Department of Psychology, Université de Montréal, Pavillon Marie-Victorin, 90 Vincent d'Indy, Montreal, QC H2V 2S9, Canada. Electronic address: sarantia.samantha.maltezos@mail.mcgill.ca.
7 Department of Psychology, Concordia University, 1455 Maisonneuve Boulevard West, Montreal, QC H3G 1M8, Canada. Electronic address: natalie.phillips@concordia.ca.
8 Department of Radiology, Université Laval, and CERVO Brain Research Center, Institut Universitaire en santé mentale de Québec, 2601 Chemin de la Canardière, Quebec City, QC G1J 2G3, Canada. Electronic address: carol.hudon@psy.ulaval.ca.

Description:

Neural correlates of resilience to the effects of hippocampal atrophy on memory.

Neuroimage Clin. 2020 Dec 07; 29:102526

Authors: Belleville S, Mellah S, Cloutier S, Dang-Vu TT, Duchesne S, Maltezos S, Phillips N, Hudon C, CIMA-Q group

Abstract

INTRODUCTION: Cognitive reserve can be defined as a property of the brain that enables an individual to sustain cognitive performance in spite of age-related neural changes. This study uses brain imaging to identify which cognitive reserve mechanisms protect against the detrimental effect of hippocampal atrophy on associative memory.

METHODS: The study included 108 older adults from the Quebec Consortium for the early identification of Alzheimer's disease. They received a magnetic resonance imaging examination to measure memory-related activations and hippocampal volume. Participants also completed a reserve-proxy questionnaire, and received a comprehensive clinical assessment.

RESULTS: Higher scores on the reserve questionnaire were associated with more activation in the right inferior temporal and left occipital fusiform gyri. The activation of the right temporal gyrus moderated the relationship between the volume of the hippocampus and face-name memory. A smaller volume was associated with weaker memory in participants with lower activation, but not in those with greater activation.

DISCUSSION: Recruitment of the temporal lobe protects against the detrimental effect of hippocampal atrophy on associative memory and contributes to cognitive reserve.

PMID: 33360019 [PubMed - as supplied by publisher]