PERFORM Publications

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Title		Authors	PubMed ID
1	A method of calculating initial DNA strand breakage following the decay of incorporated 125I.	Charlton DE, Humm JL	3257951 PHYSICS
2	Comments on strand breaks calculated from average doses to the DNA from incorporated isotopes.	Charlton DE	3353505 PHYSICS
3	Calculation of initial yields of single- and double-strand breaks in cell nuclei from electrons, protons and alpha particles.	Charlton DE, Nikjoo H, Humm JL	2569005 PHYSICS
4	Cell survival from single passages for high-LET track-segment experiments with cell monolayers.	Charlton DE, Turner MS	8248489 PHYSICS
5	Monte Carlo calculations of ion passages through brain endothelial nuclei during boron neutron capture therapy.	Charlton DE, Allen BJ	7903342 PHYSICS
6	Use of chord lengths through the nucleus to simulate the survival of mammalian cells exposed to high LET alpha-radiation.	Charlton DE, Turner MS	8609458 PHYSICS
7	Microdosimetry of haemopoietic stem cells irradiated by alpha particles from the short-lived products of 222Rn decays in fat cells and haemopoietic tissue.	Charlton DE, Utteridge TD, Beddoe AH	8648246 PHYSICS
8	The minimum Do for cell killing for alpha-particle emitters uniformly distributed in an extended medium.	Charlton DE	9611104 PHYSICS
9	The survival of monolayers of cells growing in clusters irradiated by 211At appended to the cell surfaces.	Charlton DE	10360796 PHYSICS
10	Radiation effects in spheroids of cells exposed to alpha emitters.	Charlton DE	11098858 PHYSICS

Title:	The survival of monolayers of cells growing in clusters irradiated by 211At appended to the cell surfaces.
Authors:	Charlton DE
Link:	https://www.ncbi.nlm.nih.gov/pubmed/10360796?dopt=Abstract
Publication:
Keywords:
PMID:	10360796	Category:	Radiat Res	Date Added:	2019-06-04
Dept Affiliation:	PHYSICS 1 Physics Department, Concordia University, Montreal, Quebec, Canada.

Description:

The survival of monolayers of cells growing in clusters irradiated by 211At appended to the cell surfaces.

Radiat Res. 1999 Jun;151(6):750-3

Authors: Charlton DE

Abstract

A model of cell survival is described for the case of closely packed clusters of cells growing in monolayers. For alpha-particle decays on the cell surfaces, it is shown that cross-firing between cells produces nonuniform dose distributions within the cluster and that cells in larger clusters are exposed on average to greater doses. The model is used to simulate the survival of SK-MEL-28 human melanoma cells labeled with different radiolabeled monoclonal antibodies. The survival data suggest that this cell line is more sensitive to high-LET radiation than previously thought.

PMID: 10360796 [PubMed - indexed for MEDLINE]

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