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PubMed Publications| Keyword search (4,163 papers available) |  |
"Morais JA" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | The age of obesity onset affects changes in subcutaneous adipose tissue macrophages and T cells after weight loss | Murphy J; Morais JA; Tsoukas MA; Cooke AB; Daskalopoulou SS; Santosa S; | 40831565 SOH |
| 2 | Intramyocellular lipid use is altered with exercise in males with childhood-onset obesity despite no differences in substrate oxidation | Feola S; Al-Nabelsi L; Tam BT; Near J; Morais JA; Santosa S; | 39875595 HKAP |
| 3 | Age of obesity onset affects subcutaneous adipose tissue cellularity differently in the abdominal and femoral region | Murphy J; Dera A; Morais JA; Tsoukas MA; Khor N; Sazonova T; Almeida LG; Cooke AB; Daskalopoulou SS; Tam BT; Santosa S; | 39045668 SOH |
| 4 | Senescence markers in subcutaneous preadipocytes differ in childhood- versus adult-onset obesity before and after weight loss | Murphy J; Tam BT; Kirkland JL; Tchkonia T; Giorgadze N; Pirtskhalava T; Tsoukas MA; Morais JA; Santosa S; | 37194560 PERFORM |
| 5 | Association between rs174537 FADS1 polymorphism and immune cell profiles in abdominal and femoral subcutaneous adipose tissue: an exploratory study in adults with obesity | Wang C; Murphy J; Delaney KZ; Khor N; Morais JA; Tsoukas MA; Lowry DE; Mutch DM; Santosa S; | 33595419 PERFORM |
| 6 | Sex Affects Regional Variations in Subcutaneous Adipose Tissue T Cells but not Macrophages in Adults with Obesity | Murphy J; Delaney KZ; Dam V; Tam BT; Khor N; Tsoukas MA; Morais JA; Santosa S; | 33179451 PERFORM |
| 7 | The Association Between Dietary Pattern Adherence, Cognitive Stimulating Lifestyle, and Cognitive Function Among Older Adults From the Quebec Longitudinal Study on Nutrition and Successful Aging | Parrott MD; Carmichael PH; Laurin D; Greenwood CE; Anderson ND; Ferland G; Gaudreau P; Belleville S; Morais JA; Kergoat MJ; Fiocco AJ; | 33063101 PERFORM |
| 8 | A reliable, reproducible flow cytometry protocol for immune cell quantification in human adipose tissue. | Delaney KZ, Dam V, Murphy J, Morais JA, Denis R, Atlas H, Pescarus R, Garneau PY, Santosa S | 32926866 PERFORM |
| 9 | Acetyl-CoA regulation, OXPHOS integrity and leptin level are different in females with different onsets of obesity. | Tam BT, Murphy J, Khor N, Morais JA, Santosa S | 32808657 PERFORM |
| 10 | Sex differences in the relationship between dietary pattern adherence and cognitive function among older adults: findings from the NuAge study. | D'Amico D, Parrott MD, Greenwood CE, Ferland G, Gaudreau P, Belleville S, Laurin D, Anderson ND, Kergoat MJ, Morais JA, Presse N, Fiocco AJ, | 32563260 PERFORM |
| 11 | Obesity and ageing: Two sides of the same coin. | Tam BT, Morais JA, Santosa S | 32020741 PERFORM |
| 12 | Guidelines for Gait Assessments in the Canadian Consortium on Neurodegeneration in Aging (CCNA). | Cullen S, Montero-Odasso M, Bherer L, Almeida Q, Fraser S, Muir-Hunter S, Li K, Liu-Ambrose T, McGibbon CA, McIlroy W, Middleton LE, Sarquis-Adamson Y, Beauchet O, McFadyen BJ, Morais JA, Camicioli R, Canadian Gait and Cognition Network | 29977431 ENCS |
| 13 | SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment. | Montero-Odasso M, Almeida QJ, Burhan AM, Camicioli R, Doyon J, Fraser S, Li K, Liu-Ambrose T, Middleton L, Muir-Hunter S, McIlroy W, Morais JA, Pieruccini-Faria F, Shoemaker K, Speechley M, Vasudev A, Zou GY, Berryman N, Lussier M, Vanderhaeghe L, Bherer L | 29661156 PERFORM |
| 14 | Consensus on Shared Measures of Mobility and Cognition: From the Canadian Consortium on Neurodegeneration in Aging (CCNA). | Montero-Odasso M, Almeida QJ, Bherer L, Burhan AM, Camicioli R, Doyon J, Fraser S, Muir-Hunter S, Li KZH, Liu-Ambrose T, McIlroy W, Middleton L, Morais JA, Sakurai R, Speechley M, Vasudev A, Beauchet O, Hausdorff JM, Rosano C, Studenski S, Verghese J, Canadian Gait and Cognition Network | 30101279 PERFORM |
| 15 | Use of routinely available clinical, nutritional, and functional criteria to classify cachexia in advanced cancer patients. | Vigano AAL, Morais JA, Ciutto L, Rosenthall L, di Tomasso J, Khan S, Olders H, Borod M, Kilgour RD | 27793524 HKAP |
| 16 | Intra-Abdominal Adipose Tissue Quantification by Alternative Versus Reference Methods: A Systematic Review and Meta-Analysis. | Murphy J, Bacon SL, Morais JA, Tsoukas MA, Santosa S | 31131996 PERFORM |
| Title: | Intramyocellular lipid use is altered with exercise in males with childhood-onset obesity despite no differences in substrate oxidation | ||||
| Authors: | Feola S, Al-Nabelsi L, Tam BT, Near J, Morais JA, Santosa S | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/39875595/ | ||||
| DOI: | 10.1038/s41366-025-01720-w | ||||
| Publication: | International journal of obesity (2005) | ||||
| Keywords: | |||||
| PMID: | 39875595 | Category: | Date Added: | 2025-01-29 | |
| Dept Affiliation: |
HKAP
1 Department of Health, Kinesiology, and Applied Physiology, Concordia University, Montreal, QC, Canada. 2 Metabolism, Obesity, and Nutrition Lab, School of Health, Concordia University, Montreal, QC, Canada. 3 Research Centre, Montreal North Island Integrated University Health and Social Services Centre, Montreal Sacré-Coeur Hospital (CIUSSS-NIM, HSCM), Montreal, QC, Canada. 4 Department of Sport, Physical Education and Health, Faculty of Social Sciences, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China. 5 Dr. Stephen Hui Research Centre, Faculty of Social Sciences, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China. 6 Physical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada. 7 Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada. 8 Division of Geriatric Medicine, McGill University Health Centre, Montreal, QC, Canada. 9 Department of Health, Kinesiology, and Applied Physiology, Concordia University, Montreal, QC, Canada. s.santosa@concordia.ca. 10 Metabolism, Obesity, and Nutrition Lab, School of Health, Concordia University, Montreal, QC, Canada. s.santosa@concordia.ca. 11 Research Centre, Montreal North Island Integrated University Health and Social Services Centre, Montreal Sacré-Coeur Hospital (CIUSSS-NIM, HSCM), Montreal, QC, Canada. s.santosa@concordia.ca. |
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Description: |
Objective: Compared to adulthood-onset obesity (AO), those with childhood-onset obesity (CO) are at greater risk of metabolic disease. However, the differences between these two obesity phenotypes are not clear. The aim of this study is to investigate how the age of obesity onset (CO vs. AO) affects the use of intramyocellular (IMCL) and extramyocellular (EMCL) lipids in response to exercise. Methods: Males with CO (n = 5) and AO (n = 5) were recruited. At the first study visit, body composition was measured via dual-energy x-ray absorptiometry (DEXA). Energy expenditure and substrate oxidation were measured via indirect calorimetry. Participants were provided with standardized meals for 3 days prior to the exercise study visit. At the exercise study visit, IMCL and EMCL were measured via magnetic resonance spectroscopy (MRS) before and after 90-minutes of moderate intensity cycling with indirect calorimetry. Results: Substrate oxidation at rest and during exercise was not different between groups. Post-exercise, a decrease in IMCL was observed in the AO group that was not demonstrated in the CO group. There were no changes in EMCL post-exercise in either group. Conclusions: This was the first study to compare the effects of exercise on IMCL and EMCL use in males with CO and AO. The decreases in IMCL of the AO group is similar with those observed in the literature in lean individuals. We made the novel observation that with moderate intensity cycling, males with CO do not appear to use IMCL as effectively as those with AO, suggesting perturbations in IMCL metabolism. |
