| Keyword search (4,164 papers available) | ![]() |
"Phillips N" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Biological sex and bilingualism: Its impact on risk and resilience for dementia | Calvo N; Phillips N; Bialystok E; Einstein G; | 41573422 PSYCHOLOGY |
| 2 | Hearing loss is associated with decreased default-mode network connectivity in individuals with mild cognitive impairment | Grant N; Phillips N; | 40567819 PSYCHOLOGY |
| 3 | Connected speech profiles in mild cognitive impairment reflect global cognition | Pellerin S; Houzé B; Bedetti C; Phillips N; Brambati SM; | 40232260 PSYCHOLOGY |
| 4 | Biomarkers | Grant N; Phillips N; | 39785420 CONCORDIA |
| 5 | Clinical Manifestations | Phillips N; Best PT; Grant N; Kabir A; | 39750307 CONCORDIA |
| 6 | Clinical Manifestations | Calvo N; Siddiqui R; Phillips N; Einstein G; | 39750698 CONCORDIA |
| 7 | Basic Science and Pathogenesis | Lima BS; Rosa-Neto P; Phillips N; Borrie M; Roncero CT; Lahiri D; Dori D; Chertkow H; | 39751468 CONCORDIA |
| 8 | Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA) | Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; Bélanger N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello C; Cynader M; Dang-Vu T; Das S; Dixon RA; Ducharme S; Einstein G; Evans AC; Fahnestock M; Feldman H; Ferland G; Finger E; Fisk JD; Fogarty J; Fon E; Gan-Or Z; Gauthier S; Greenwood C; Henri-Bellemare C; Herrmann N; Hogan DB; Hsiung R; Itzhak I; Jacklin K; Lanctôt K; Lim A; MacKenzie I; Masellis M; Maxwell C; McAiney C; McGilton K; McLaurin J; Mihailidis A; Mohades Z; Montero-Odasso M; Morgan D; Naglie G; Nygaard H; O' Connell M; Petersen R; Pilon R; Rajah MN; Rapoport M; Roach P; Robillard JM; Rogaeva E; Rosa-Neto P; Rylett J; Sadavoy J; St George-Hyslop P; Seitz D; Smith E; Stefanovic B; Vedel I; Walker JD; Wellington C; Whitehead V; Wittich W; | 39636028 HKAP |
| 9 | Development and validation of risk of CPS decline (RCD): a new prediction tool for worsening cognitive performance among home care clients in Canada | Guthrie DM; Williams N; O' Rourke HM; Orange JB; Phillips N; Pichora-Fuller MK; Savundranayagam MY; Sutradhar R; | 38041046 CRDH |
| 10 | Associations Between Cardiovascular Risk Factors and Audiometric Hearing: Findings From the Canadian Longitudinal Study on Aging | Mick PT; Kabir R; Pichora-Fuller MK; Jones C; Moxham L; Phillips N; Urry E; Wittich W; | 37122082 PSYCHOLOGY |
| 11 | The association between information and communication technologies, loneliness and social connectedness: A scoping review | Petersen B; Khalili-Mahani N; Murphy C; Sawchuk K; Phillips N; Li KZH; Hebblethwaite S; | 37034933 PSYCHOLOGY |
| 12 | Consensus Statement Regarding the Application of Biogen to Health Canada for Approval of Aducanumab | Chertkow H; Rockwood K; Hogan DB; Phillips N; Montero-Odasso M; Amanullah S; Black S; Bocti C; Borrie M; Feldman H; Freedman M; Hsiung R; Kirk A; Masellis M; Nygaard H; Rajji T; Verret L; | 34912492 PSYCHOLOGY |
| 13 | Neural correlates of resilience to the effects of hippocampal atrophy on memory. | Belleville S, Mellah S, Cloutier S, Dang-Vu TT, Duchesne S, Maltezos S, Phillips N, Hudon C, CIMA-Q group | 33360019 HKAP |
| 14 | CCCDTD5 recommendations on early non cognitive markers of dementia: A Canadian consensus | Montero-Odasso M; Pieruccini-Faria F; Ismail Z; Li K; Lim A; Phillips N; Kamkar N; Sarquis-Adamson Y; Speechley M; Theou O; Verghese J; Wallace L; Camicioli R; | 33094146 CRDH |
| 15 | The Prevalence of Hearing, Vision, and Dual Sensory Loss in Older Canadians: An Analysis of Data from the Canadian Longitudinal Study on Aging. | Mick PT, Hämäläinen A, Kolisang L, Pichora-Fuller MK, Phillips N, Guthrie D, Wittich W | 32546290 PSYCHOLOGY |
| 16 | Sensory-cognitive associations are only weakly mediated or moderated by social factors in the Canadian Longitudinal Study on Aging. | Hämäläinen A, Phillips N, Wittich W, Pichora-Fuller MK, Mick P | 31873079 PSYCHOLOGY |
| 17 | Evidence of a Relation Between Hippocampal Volume, White Matter Hyperintensities, and Cognition in Subjective Cognitive Decline and Mild Cognitive Impairment | Caillaud M; Hudon C; Boller B; Brambati S; Duchesne S; Lorrain D; Gagnon JF; Maltezos S; Mellah S; Phillips N; Belleville S; | 31758692 CRDH |
| 18 | Associations between sensory loss and social networks, participation, support, and loneliness: Analysis of the Canadian Longitudinal Study on Aging. | Mick P, Parfyonov M, Wittich W, Phillips N, Guthrie D, Kathleen Pichora-Fuller M | 29358266 PSYCHOLOGY |
| 19 | The Effects of Age and Hearing Loss on Dual-Task Balance and Listening. | Bruce H, Aponte D, St-Onge N, Phillips N, Gagné JP, Li KZH | 28486677 PERFORM |
| Title: | CCCDTD5 recommendations on early non cognitive markers of dementia: A Canadian consensus | ||||
| Authors: | Montero-Odasso M, Pieruccini-Faria F, Ismail Z, Li K, Lim A, Phillips N, Kamkar N, Sarquis-Adamson Y, Speechley M, Theou O, Verghese J, Wallace L, Camicioli R | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/33094146/ | ||||
| DOI: | 10.1002/trc2.12068 | ||||
| Publication: | Alzheimer s & dementia (New York, N. Y.) | ||||
| Keywords: | behavior; biomarker; cognitive impairment; dementia; frailty; gait; hearing; olfaction; parkinsonism; prediction; risk; sleep; vision; | ||||
| PMID: | 33094146 | Category: | Alzheimers Dement (N Y) | Date Added: | 2020-10-24 |
| Dept Affiliation: |
CRDH
1 Gait and Brain Laboratory Parkwood Institute Lawson Health Research Institute London Ontario Canada. 2 Division of Geriatric Medicine Department of Medicine Schulich School of Medicine and Dentistry London Ontario Canada. 3 Department of Epidemiology and Biostatistics University of Western Ontario London Ontario Canada. 4 Departments of Psychiatry Clinical Neurosciences and Community Health Sciences Hotchkiss Brain Institute and O'Brien Institute for Public Health University of Calgary Calgary Alberta Canada. 5 Centre for Research in Human Development Concordia University Montreal Quebec Canada. 6 Department of Psychology Concordia University Quebec Canada. 7 Division of Neurology Department of Medicine Sunnybrook Health Sciences Centre Toronto Ontario Canada. 8 School of Physiotherapy Dalhousie University Halifax Nova Scotia Canada. 9 Department of Medicine Dalhousie University Halifax Nova Scotia Canada. 10 Department of Neurology Albert Einstein College of Medicine Bronx New York USA. 11 Division of Neurology Department of Medicine University of Alberta Edmonton Alberta Canada. |
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Description: |
Introduction: Cognitive impairment is the hallmark of Alzheimer's disease (AD) and related dementias. However, motor decline has been recently described as a prodromal state that can help to detect at-risk individuals. Similarly, sensory changes, sleep and behavior disturbances, and frailty have been associated with higher risk of developing dementia. These clinical findings, together with the recognition that AD pathology precedes the diagnosis by many years, raises the possibility that non-cognitive changes may be early and non-invasive markers for AD or, even more provocatively, that treating non-cognitive aspects may help to prevent or treat AD and related dementias. Methods: A subcommittee of the Canadian Consensus Conference on Diagnosis and Treatment of Dementia reviewed areas of emerging evidence for non-cognitive markers of dementia. We examined the literature for five non-cognitive domains associated with future dementia: motor, sensory (hearing, vision, olfaction), neuro-behavioral, frailty, and sleep. The Grading of Recommendations Assessment, Development, and Evaluation system was used to assign the strength of the evidence and quality of the recommendations. We provide recommendations to primary care clinics and to specialized memory clinics, answering the following main questions: (1) What are the non-cognitive and functional changes associated with risk of developing dementia? and (2) What is the evidence that sensory, motor, behavioral, sleep, and frailty markers can serve as potential predictors of dementia? Results: Evidence supported that gait speed, dual-task gait speed, grip strength, frailty, neuropsychiatric symptoms, sleep measures, and hearing loss are predictors of dementia. There was insufficient evidence for recommending assessing olfactory and vision impairments as a predictor of dementia. Conclusions: Non-cognitive markers can assist in identifying people at risk for cognitive decline or dementia. These non-cognitive markers may represent prodromal symptoms and several of them are potentially amenable to treatment that might delay the onset of cognitive decline. |



