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PubMed Publications| Keyword search (4,163 papers available) |  |
"Phillips N" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Biological sex and bilingualism: Its impact on risk and resilience for dementia | Calvo N; Phillips N; Bialystok E; Einstein G; | 41573422 PSYCHOLOGY |
| 2 | Hearing loss is associated with decreased default-mode network connectivity in individuals with mild cognitive impairment | Grant N; Phillips N; | 40567819 PSYCHOLOGY |
| 3 | Connected speech profiles in mild cognitive impairment reflect global cognition | Pellerin S; Houzé B; Bedetti C; Phillips N; Brambati SM; | 40232260 PSYCHOLOGY |
| 4 | Biomarkers | Grant N; Phillips N; | 39785420 CONCORDIA |
| 5 | Clinical Manifestations | Phillips N; Best PT; Grant N; Kabir A; | 39750307 CONCORDIA |
| 6 | Clinical Manifestations | Calvo N; Siddiqui R; Phillips N; Einstein G; | 39750698 CONCORDIA |
| 7 | Basic Science and Pathogenesis | Lima BS; Rosa-Neto P; Phillips N; Borrie M; Roncero CT; Lahiri D; Dori D; Chertkow H; | 39751468 CONCORDIA |
| 8 | Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA) | Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; Bélanger N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello C; Cynader M; Dang-Vu T; Das S; Dixon RA; Ducharme S; Einstein G; Evans AC; Fahnestock M; Feldman H; Ferland G; Finger E; Fisk JD; Fogarty J; Fon E; Gan-Or Z; Gauthier S; Greenwood C; Henri-Bellemare C; Herrmann N; Hogan DB; Hsiung R; Itzhak I; Jacklin K; Lanctôt K; Lim A; MacKenzie I; Masellis M; Maxwell C; McAiney C; McGilton K; McLaurin J; Mihailidis A; Mohades Z; Montero-Odasso M; Morgan D; Naglie G; Nygaard H; O' Connell M; Petersen R; Pilon R; Rajah MN; Rapoport M; Roach P; Robillard JM; Rogaeva E; Rosa-Neto P; Rylett J; Sadavoy J; St George-Hyslop P; Seitz D; Smith E; Stefanovic B; Vedel I; Walker JD; Wellington C; Whitehead V; Wittich W; | 39636028 HKAP |
| 9 | Development and validation of risk of CPS decline (RCD): a new prediction tool for worsening cognitive performance among home care clients in Canada | Guthrie DM; Williams N; O' Rourke HM; Orange JB; Phillips N; Pichora-Fuller MK; Savundranayagam MY; Sutradhar R; | 38041046 CRDH |
| 10 | Associations Between Cardiovascular Risk Factors and Audiometric Hearing: Findings From the Canadian Longitudinal Study on Aging | Mick PT; Kabir R; Pichora-Fuller MK; Jones C; Moxham L; Phillips N; Urry E; Wittich W; | 37122082 PSYCHOLOGY |
| 11 | The association between information and communication technologies, loneliness and social connectedness: A scoping review | Petersen B; Khalili-Mahani N; Murphy C; Sawchuk K; Phillips N; Li KZH; Hebblethwaite S; | 37034933 PSYCHOLOGY |
| 12 | Consensus Statement Regarding the Application of Biogen to Health Canada for Approval of Aducanumab | Chertkow H; Rockwood K; Hogan DB; Phillips N; Montero-Odasso M; Amanullah S; Black S; Bocti C; Borrie M; Feldman H; Freedman M; Hsiung R; Kirk A; Masellis M; Nygaard H; Rajji T; Verret L; | 34912492 PSYCHOLOGY |
| 13 | Neural correlates of resilience to the effects of hippocampal atrophy on memory. | Belleville S, Mellah S, Cloutier S, Dang-Vu TT, Duchesne S, Maltezos S, Phillips N, Hudon C, CIMA-Q group | 33360019 HKAP |
| 14 | CCCDTD5 recommendations on early non cognitive markers of dementia: A Canadian consensus | Montero-Odasso M; Pieruccini-Faria F; Ismail Z; Li K; Lim A; Phillips N; Kamkar N; Sarquis-Adamson Y; Speechley M; Theou O; Verghese J; Wallace L; Camicioli R; | 33094146 CRDH |
| 15 | The Prevalence of Hearing, Vision, and Dual Sensory Loss in Older Canadians: An Analysis of Data from the Canadian Longitudinal Study on Aging. | Mick PT, Hämäläinen A, Kolisang L, Pichora-Fuller MK, Phillips N, Guthrie D, Wittich W | 32546290 PSYCHOLOGY |
| 16 | Sensory-cognitive associations are only weakly mediated or moderated by social factors in the Canadian Longitudinal Study on Aging. | Hämäläinen A, Phillips N, Wittich W, Pichora-Fuller MK, Mick P | 31873079 PSYCHOLOGY |
| 17 | Evidence of a Relation Between Hippocampal Volume, White Matter Hyperintensities, and Cognition in Subjective Cognitive Decline and Mild Cognitive Impairment | Caillaud M; Hudon C; Boller B; Brambati S; Duchesne S; Lorrain D; Gagnon JF; Maltezos S; Mellah S; Phillips N; Belleville S; | 31758692 CRDH |
| 18 | Associations between sensory loss and social networks, participation, support, and loneliness: Analysis of the Canadian Longitudinal Study on Aging. | Mick P, Parfyonov M, Wittich W, Phillips N, Guthrie D, Kathleen Pichora-Fuller M | 29358266 PSYCHOLOGY |
| 19 | The Effects of Age and Hearing Loss on Dual-Task Balance and Listening. | Bruce H, Aponte D, St-Onge N, Phillips N, Gagné JP, Li KZH | 28486677 PERFORM |
| Title: | Hearing loss is associated with decreased default-mode network connectivity in individuals with mild cognitive impairment | ||||
| Authors: | Grant N, Phillips N | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/40567819/ | ||||
| DOI: | 10.1016/j.ynirp.2023.100188 | ||||
| Publication: | Neuroimage. Reports | ||||
| Keywords: | Default-mode network; Functional connectivity; Hearing loss; Mild cognitive impairment; Resting-state; | ||||
| PMID: | 40567819 | Category: | Date Added: | 2025-06-26 | |
| Dept Affiliation: |
PSYCHOLOGY
1 Department of Psychology, Concordia University, Montreal Quebec, Canada. 2 Centre for Research on Human Development, Concordia University, Montreal Quebec, Canada. 3 engAGE Centre for Research on Aging, Concordia University, Montreal Quebec, Canada. 4 Centre for Research on the Brain Language and Music, Montreal Quebec, Canada. 5 Canadian Consortium on Neurodegeneration in Aging, Canada. 6 Lady Davis Institute for Medical Research at the Jewish General Hospital, Montreal Quebec, Canada. |
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Description: |
Mild cognitive impairment (MCI) and hearing loss (HL) have been separately associated with increased dementia risk. These highly co-occurring dementia risk factors are associated with aberrant functional brain connectivity. In individuals with HL aberrant functional connectivity has been associated with cognitive impairment. In individuals with MCI, aberrant brain connectivity has been associated with severity of cognitive impairment and conversion to dementia. Despite the high prevalence of HL in individuals with MCI, the relationship between the two is understudied, especially in the context of functional connectivity. Participants: include 94 older adults with MCI. Hearing measures include pure-tone hearing thresholds and speech-reception thresholds. In analyses with pure-tone hearing loss, participants were classified as having normal hearing (n = 60) or hearing loss (n = 34) based on a pure-tone screening protocol. We used independent component analyses on resting-state functional magnetic resonance imaging data to identify the default-mode network (DMN). Analysis of variance with covariate control was used to investigate DMN connectivity differences between the normally hearing individuals with MCI and individuals with MCI and pure-tone HL. A linear regression was used to investigate the relationship between speech-reception threshold and DMN connectivity in the whole sample.Compared to those with MCI and normal hearing, those with MCI and pure-tone HL had decreased connectivity between the DMN and the caudate and thalamus. There was no difference in DMN connectivity as a function of speech-reception threshold.Our findings indicate that in individuals with MCI, HL is associated with decreased connectivity between the DMN and regions important for sensory and cognitive processing. This suggests that the increased risk for cognitive decline and dementia in individuals with HL may be due to decreased DMN connectivity in individuals with HL. |
