PERFORM Publications

Keyword search (4,163 papers available)

Title		Authors	PubMed ID
1	A synergistic approach to rapid stabilization and immobilization of crude oil-contaminated clayey sand using calcium chloride and sodium silicate	Rajaei E; Elektorowicz M; Baker MB;	41391286 ENCS
2	Pitavastatin Calcium Confers Fungicidal Properties to Fluconazole by Inhibiting Ubiquinone Biosynthesis and Generating Reactive Oxygen Species	Li W; Feng Y; Feng Z; Wang L; Whiteway M; Lu H; Jiang Y;	38929106 BIOLOGY
3	The caleosin RD20/CLO3 regulates lateral root development in response to abscisic acid and regulates flowering time in conjunction with the caleosin CLO7	Brunetti SC; Arseneault MKM; Gulick PJ;	37812854 BIOLOGY
4	Evaluation of Increasing Dairy Intake on Bone Density in Postpubertal Youth: A Randomized Controlled Trial Using Motivational Interviewing	Slim M; Vanstone CA; Morin SN; Rahme E; Bacon SL; Weiler HA;	36967160 HKAP
5	Overview of Sigma-1R Subcellular Specific Biological Functions and Role in Neuroprotection	Véronik Lachance	36768299 CSBN
6	Calcium activity is a degraded estimate of spikes	Hart EE; Gardner MPH; Panayi MC; Kahnt T; Schoenbaum G;	36368324 PSYCHOLOGY
7	Atorvastatin lowers serum calcium levels in lithium-users: results from a randomized controlled trial	Soh JF; Bodenstein K; Yu OHY; Linnaranta O; Renaud S; Mahdanian A; Su CL; Mucsi I; Mulsant B; Herrmann N; Rajji T; Beaulieu S; Sekhon H; Rej S;	36153583 PSYCHOLOGY
8	Evaluation of Increasing Dairy Intake on Bone Density in Post-pubertal Youth: A Randomized Controlled Trial Using Motivational Interviewing	Slim M; Vanstone CA; Morin SN; Rahme E; Bacon SL; Weiler HA;	35015862 HKAP
9	The stress induced caleosin, RD20/CLO3, acts as a negative regulator of GPA1 in Arabidopsis	Brunetti SC; Arseneault MKM; Wright JA; Wang Z; Ehdaeivand MR; Lowden MJ; Rivoal J; Khalil HB; Garg G; Gulick PJ;	34599731 BIOLOGY
10	Bioprinting of Adult Dorsal Root Ganglion (DRG) Neurons Using Laser-Induced Side Transfer (LIST)	Roversi K; Ebrahimi Orimi H; Falchetti M; Lummertz da Rocha E; Talbot S; Boutopoulos C;	34442487 ENCS
11	All-optical approaches to studying psychiatric disease	Lafferty CK; Christinck TD; Britt JP;	34314828 CSBN
12	Calcium-calcineurin signaling pathway in Candida albicans: A potential drug target	Li W; Shrivastava M; Lu H; Jiang Y;	33989979 BIOLOGY
13	Transendothelial Perforations and the Sphere of Influence of Single-Site Sonoporation.	Helfield B, Chen X, Watkins SC, Villanueva FS	32402675 BIOLOGY
14	RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans.	Xu H, Fang T, Omran RP, Whiteway M, Jiang L	31900175 BIOLOGY
15	Cue-Evoked Dopamine Neuron Activity Helps Maintain but Does Not Encode Expected Value.	Mendoza JA, Lafferty CK, Yang AK, Britt JP	31693885 CSBN

Title:	Cue-Evoked Dopamine Neuron Activity Helps Maintain but Does Not Encode Expected Value.
Authors:	Mendoza JA, Lafferty CK, Yang AK, Britt JP
Link:	https://www.ncbi.nlm.nih.gov/pubmed/31693885?dopt=Abstract
DOI:	10.1016/j.celrep.2019.09.077
Publication:	Cell reports
Keywords:	calcium imaging; dopamine; expected value; motivation; optogenetics; overexpectation; reinforcement learning; reward prediction error; ventral tegmental area;
PMID:	31693885	Category:	Cell Rep	Date Added:	2019-11-07
Dept Affiliation:	CSBN 1 Department of Psychology, McGill University, Montreal, QC H3A 1B1, Canada; Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, QC H4B 1R6, Canada. 2 Integrated Program in Neuroscience, McGill University, Montreal, QC H3A 2B4, Canada; Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, QC H4B 1R6, Canada. 3 Department of Psychology, McGill University, Montreal, QC H3A 1B1, Canada; Integrated Program in Neuroscience, McGill University, Montreal, QC H3A 2B4, Canada; Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, QC H4B 1R6, Canada. Electronic address: jonathan.britt@mcgill.ca.

Description:

Cue-Evoked Dopamine Neuron Activity Helps Maintain but Does Not Encode Expected Value.

Cell Rep. 2019 Nov 05;29(6):1429-1437.e3

Authors: Mendoza JA, Lafferty CK, Yang AK, Britt JP

Abstract

Cue-evoked midbrain dopamine (DA) neuron activity reflects expected value, but its influence on reward assessment is unclear. In mice performing a trial-based operant task, we test if bidirectional manipulations of cue or operant-associated DA neuron activity drive learning as a result of under- or overexpectation of reward value. We target optogenetic manipulations to different components of forced trials, when only one lever is presented, and assess lever biases on choice trials in the absence of photomanipulation. Although lever biases are demonstrated to be flexible and sensitive to changes in expected value, augmentation of cue or operant-associated DA signaling does not significantly alter choice behavior, and blunting DA signaling during any component of the forced trials reduces choice trial responses on the associated lever. These data suggest cue-evoked DA helps maintain cue-value associations but does not encode expected value as to set the benchmark against which received reward is judged.

PMID: 31693885 [PubMed - in process]

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