Keyword search (3,447 papers available)


The priming effect of food persists following blockade of dopamine receptors.

Author(s): Evangelista C, Hantson A, Shams WM, Almey A, Pileggi M, Voisard JR, Boulos V, Al-Qadri Y, Gonzalez Cautela BV, Zhou FX, Duchemin J, Habrich ...

Eur J Neurosci. 2019 Jul 27;: Authors: Evangelista C, Hantson A, Shams WM, Almey A, Pileggi M, Voisard JR, Boulos V, Al-Qadri Y, Gonzalez Cautela BV, Zhou FX, Duchemin J, Habrich A, Tito N, Koumro...

Article GUID: 31350860
Estrogen receptor α and G-protein coupled estrogen receptor 1 are localized to GABAergic neurons in the dorsal striatum.

Author(s): Almey A, Milner TA, Brake WG

Neurosci Lett. 2016 05 27;622:118-23 Authors: Almey A, Milner TA, Brake WG

Article GUID: 27080432
High estrogen and chronic haloperidol lead to greater amphetamine-induced BOLD activation in awake, amphetamine-sensitized female rats.

Author(s): Madularu D, Kulkarni P, Yee JR, Kenkel WM, Shams WM, Ferris CF, Brake WG

Horm Behav. 2016 06;82:56-63 Authors: Madularu D, Kulkarni P, Yee JR, Kenkel WM, Shams WM, Ferris CF, Brake WG

Article GUID: 27154458
Modulation of spatial and response strategies by phase of the menstrual cycle in women tested in a virtual navigation task.

Author(s): Hussain D, Hanafi S, Konishi K, Brake WG, Bohbot VD

Psychoneuroendocrinology. 2016 08;70:108-17 Authors: Hussain D, Hanafi S, Konishi K, Brake WG, Bohbot VD

Article GUID: 27213559
17β-Estradiol infusions into the dorsal striatum rapidly increase dorsal striatal dopamine release in vivo.

Author(s): Shams WM, Sanio C, Quinlan MG, Brake WG

Neuroscience. 2016 08 25;330:162-70 Authors: Shams WM, Sanio C, Quinlan MG, Brake WG

Article GUID: 27256507
Interactions between estradiol and haloperidol on perseveration and reversal learning in amphetamine-sensitized female rats.

Author(s): Almey A, Arena L, Oliel J, Shams WM, Hafez N, Mancinelli C, Henning L, Tsanev A, Brake WG

Horm Behav. 2017 03;89:113-120 Authors: Almey A, Arena L, Oliel J, Shams WM, Hafez N, Mancinelli C, Henning L, Tsanev A, Brake WG

Article GUID: 28062232
17β-estradiol locally increases phasic dopamine release in the dorsal striatum.

Author(s): Shams WM, Cossette MP, Shizgal P, Brake WG

Neurosci Lett. 2018 02 05;665:29-32 Authors: Shams WM, Cossette MP, Shizgal P, Brake WG

Article GUID: 29175028
Modulatory effect of 17-β estradiol on performance of ovariectomized rats on the Shock-Probe test.

Author(s): Gervais NJ, Jacob S, Brake WG, Mumby DG

Physiol Behav. 2014 May 28;131:129-35 Authors: Gervais NJ, Jacob S, Brake WG, Mumby DG

Article GUID: 24768650
Changes in brain volume in response to estradiol levels, amphetamine sensitization and haloperidol treatment in awake female rats.

Author(s): Madularu D, Kulkarni P, Ferris CF, Brake WG

Brain Res. 2015 Aug 27;1618:100-10 Authors: Madularu D, Kulkarni P, Ferris CF, Brake WG

Article GUID: 26032742
Attenuation of dendritic spine density in the perirhinal cortex following 17β-Estradiol replacement in the rat.

Author(s): Gervais NJ, Mumby DG, Brake WG

Hippocampus. 2015 Nov;25(11):1212-6 Authors: Gervais NJ, Mumby DG, Brake WG

Article GUID: 26104963
Ovarian steroids alter dopamine receptor populations in the medial preoptic area of female rats: implications for sexual motivation, desire, and behaviour.

Author(s): Graham MD, Gardner Gregory J, Hussain D, Brake WG, Pfaus JG

Eur J Neurosci. 2015 Dec;42(12):3138-48 Authors: Graham MD, Gardner Gregory J, Hussain D, Brake WG, Pfaus JG

Article GUID: 26536143
High Oestradiol Replacement Reverses Response Memory Bias in Ovariectomised Female Rats Regardless of Dopamine Levels in the Dorsal Striatum.

Author(s): Hussain D, Cossette MP, Brake WG

J Neuroendocrinol. 2016 05;28(5): Authors: Hussain D, Cossette MP, Brake WG

Article GUID: 26929121
Intra-perirhinal cortex administration of estradiol, but not an ERβ agonist, modulates object-recognition memory in ovariectomized rats.

Author(s): Gervais NJ, Hamel LM, Brake WG, Mumby DG

Neurobiol Learn Mem. 2016 09;133:89-99 Authors: Gervais NJ, Hamel LM, Brake WG, Mumby DG

Article GUID: 27321161
Title:Ovarian steroids alter dopamine receptor populations in the medial preoptic area of female rats: implications for sexual motivation, desire, and behaviour.
Authors:Graham MD,  Gardner Gregory J,  Hussain D,  Brake WG,  Pfaus JG
Link:https://www.ncbi.nlm.nih.gov/pubmed/26536143?dopt=Abstract
Category:Eur J Neurosci
PMID:26536143
Dept Affiliation: PSYCHOLOGY
1 Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, 7141 Sherbrooke W., Montréal, QC, Canada, H4B 1R6.

Description:

Ovarian steroids alter dopamine receptor populations in the medial preoptic area of female rats: implications for sexual motivation, desire, and behaviour.

Eur J Neurosci. 2015 Dec;42(12):3138-48

Authors: Graham MD, Gardner Gregory J, Hussain D, Brake WG, Pfaus JG

Abstract

Dopamine (DA) transmission in the medial preoptic area (mPOA) plays a critical role in the control of appetitive sexual behaviour in the female rat. We have shown previously that a DA D1 receptor (D1R)-mediated excitatory state appears to occur in females primed with estradiol benzoate (EB) and progesterone (P), whereas a DA D2 receptor (D2R)-mediated inhibitory state appears to occur in females primed only with EB. The present experiment employed three techniques to better understand what changes occur to DA receptors (DARs) in the mPOA under different hormonal profiles. Ovariectomized females were randomly assigned to one of three steroid treatment groups: EB + P (10 and 500 µg, respectively), EB + Oil, or the control (Oil + Oil), with hormone injections administered at 48 and 4 h prior to euthanizing. First, the number of neurons in the mPOA that contained D1R or D2R was assessed using immunohistochemistry. Second, the mPOA and two control areas (the prelimbic cortex and caudate putamen) were analysed for DAR protein levels using western blot, and DAR functional binding levels using autoradiography. Ovarian steroid hormones affected the two DAR subtypes in opposite ways in the mPOA. All three techniques supported previous behavioural findings that females primed with EB have a lower D1R : D2R ratio, and thus a D2R-mediated system, and females primed with EB + P have a higher D1R : D2R ratio, and thus a D1R-mediated system. This provides strong evidence for a DA-driven pathway of female sexual motivation, desire, and behaviour that is modified by different hormone priming regimens.

PMID: 26536143 [PubMed - indexed for MEDLINE]