Keyword search (3,619 papers available)


Molecular mechanisms of neurodegeneration in the entorhinal cortex that underlie its selective vulnerability during the pathogenesis of Alzheimer's disease.

Author(s): Olajide OJ, Suvanto ME, Chapman CA

The entorhinal cortex (EC) is a vital component of the medial temporal lobe, and its contributions to cognitive processes and memory formation are supported through its extensive interconnections with the hippocampal formation. During the pathogenesis of Al...

Article GUID: 33495355
State-Dependent Entrainment of Prefrontal Cortex Local Field Potential Activity Following Patterned Stimulation of the Cerebellar Vermis.

Author(s): Tremblay SA, Chapman CA, Courtemanche R

Front Syst Neurosci. 2019;13:60 Authors: Tremblay SA, Chapman CA, Courtemanche R

Article GUID: 31736718
Heterosynaptic modulation of evoked synaptic potentials in layer II of the entorhinal cortex by activation of the parasubiculum.

Author(s): Sparks DW, Chapman CA

J Neurophysiol. 2016 08 01;116(2):658-70 Authors: Sparks DW, Chapman CA

Article GUID: 27146979
Gap Junction Modulation of Low-Frequency Oscillations in the Cerebellar Granule Cell Layer.

Author(s): Robinson JC, Chapman CA, Courtemanche R

Cerebellum. 2017 08;16(4):802-811 Authors: Robinson JC, Chapman CA, Courtemanche R

Article GUID: 28421552
Exposure to cues associated with palatable food reward results in a dopamine D₂ receptor-dependent suppression of evoked synaptic responses in the entorhinal cortex.

Author(s): Hutter JA, Chapman CA

Behav Brain Funct. 2013 Oct 04;9:37 Authors: Hutter JA, Chapman CA

Article GUID: 24093833
Dopaminergic enhancement of excitatory synaptic transmission in layer II entorhinal neurons is dependent on D₁-like receptor-mediated signaling.

Author(s): Glovaci I, Caruana DA, Chapman CA

Neuroscience. 2014 Jan 31;258:74-83 Authors: Glovaci I, Caruana DA, Chapman CA

Article GUID: 24220689
Diurnal influences on electrophysiological oscillations and coupling in the dorsal striatum and cerebellar cortex of the anesthetized rat.

Author(s): Frederick A, Bourget-Murray J, Chapman CA, Amir S, Courtemanche R

Front Syst Neurosci. 2014;8:145 Authors: Frederick A, Bourget-Murray J, Chapman CA, Amir S, Courtemanche R

Article GUID: 25309348
Activation of Phosphatidylinositol-Linked Dopamine Receptors Induces a Facilitation of Glutamate-Mediated Synaptic Transmission in the Lateral Entorhinal Cortex.

Author(s): Glovaci I, Chapman CA

PLoS One. 2015;10(7):e0131948 Authors: Glovaci I, Chapman CA

Article GUID: 26133167
Optogenetic Activation of the Infralimbic Cortex Suppresses the Return of Appetitive Pavlovian-Conditioned Responding Following Extinction.

Author(s): Villaruel FR, Lacroix F, Sanio C, Sparks DW, Chapman CA, Chaudhri N

Cereb Cortex. 2018 Dec 01;28(12):4210-4221 Authors: Villaruel FR, Lacroix F, Sanio C, Sparks DW, Chapman CA, Chaudhri N

Article GUID: 29045570
Dopamine suppresses persistent firing in layer III lateral entorhinal cortex neurons.

Author(s): Batallán-Burrowes AA, Chapman CA

Neurosci Lett. 2018 05 01;674:70-74 Authors: Batallán-Burrowes AA, Chapman CA

Article GUID: 29524644
The role of the paraventricular nucleus of the thalamus in the augmentation of heroin seeking induced by chronic food restriction.

Author(s): Chisholm A, Iannuzzi J, Rizzo D, Gonzalez N, Fortin É, Bumbu A, Batallán Burrowes AA, Chapman CA, Shalev U

Addict Biol. 2019 Jan 09;: Authors: Chisholm A, Iannuzzi J, Rizzo D, Gonzalez N, Fortin É, Bumbu A, Batallán Burrowes AA, Chapman CA, Shalev U

Article GUID: 30623532
Serotonin 5-HT1A Receptor-Mediated Reduction of Excitatory Synaptic Transmission in Layers II/III of the Parasubiculum.

Author(s): Carter F, Chapman CA

Neuroscience. 2019 May 15;406:325-332 Authors: Carter F, Chapman CA

Article GUID: 30902681
Dopamine induces release of calcium from internal stores in layer II lateral entorhinal cortex fan cells.

Author(s): Glovaci I, Chapman CA

Cell Calcium. 2019 Apr 10;80:103-111 Authors: Glovaci I, Chapman CA

Article GUID: 30999216
Title:State-Dependent Entrainment of Prefrontal Cortex Local Field Potential Activity Following Patterned Stimulation of the Cerebellar Vermis.
Authors:Tremblay SA,  Chapman CA,  Courtemanche R
Link:https://www.ncbi.nlm.nih.gov/pubmed/31736718?dopt=Abstract
DOI:10.3389/fnsys.2019.00060
Category:Front Syst Neurosci
PMID:31736718
Dept Affiliation: HKAP
1 Department of Health, Kinesiology, and Applied Physiology, Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, QC, Canada.
2 Department of Psychology, Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, QC, Canada.

Description:

State-Dependent Entrainment of Prefrontal Cortex Local Field Potential Activity Following Patterned Stimulation of the Cerebellar Vermis.

Front Syst Neurosci. 2019;13:60

Authors: Tremblay SA, Chapman CA, Courtemanche R

Abstract

The cerebellum is involved in sensorimotor, cognitive, and emotional functions through cerebello-cerebral connectivity. Cerebellar neurostimulation thus likely affects cortical circuits, as has been shown in studies using cerebellar stimulation to treat neurological disorders through modulation of frontal EEG oscillations. Here we studied the effects of different frequencies of cerebellar stimulation on oscillations and coherence in the cerebellum and prefrontal cortex in the urethane-anesthetized rat. Local field potentials were recorded in the right lateral cerebellum (Crus I/II) and bilaterally in the prefrontal cortex (frontal association area, FrA) in adult male Sprague-Dawley rats. Stimulation was delivered to the cerebellar vermis (lobule VII) using single pulses (0.2 Hz for 60 s), or repeated pulses at 1 Hz (30 s), 5 Hz (10 s), 25 Hz (2 s), and 50 Hz (1 s). Effects of stimulation were influenced by the initial state of EEG activity which varies over time during urethane-anesthesia; 1 Hz stimulation was more effective when delivered during the slow-wave state (Stage 1), while stimulation with single-pulse, 25, and 50 Hz showed stronger effects during the activated state (Stage 2). Single-pulses resulted in increases in oscillatory power in the delta and theta bands for the cerebellum, and in frequencies up to 80 Hz in cortical sites. 1 Hz stimulation induced a decrease in 0-30 Hz activity and increased activity in the 30-200 Hz range, in the right FrA. 5 Hz stimulation reduced power in high frequencies in Stage 1 and induced mixed effects during Stage 2.25 Hz stimulation increased cortical power at low frequencies during Stage 2, and increased power in higher frequency bands during Stage 1. Stimulation at 50 Hz increased delta-band power in all recording sites, with the strongest and most rapid effects in the cerebellum. 25 and 50 Hz stimulation also induced state-dependent effects on cerebello-cortical and cortico-cortical coherence at high frequencies. Cerebellar stimulation can therefore entrain field potential activity in the FrA and drive synchronization of cerebello-cortical and cortico-cortical networks in a frequency-dependent manner. These effects highlight the role of the cerebellar vermis in modulating large-scale synchronization of neural networks in non-motor frontal cortex.

PMID: 31736718 [PubMed]