Keyword search (3,448 papers available)


Cue-alcohol associative learning in female rats.

Author(s): Cofresí RU, Monfils MH, Chaudhri N, Gonzales RA, Lee HJ

The ability of environmental cues to trigger alcohol-seeking behaviors is believed to facilitate problematic alcohol use. We previously showed that the development of this cue-evoked alcohol approach reflects cue-alcohol learning and memory in the adult mal...

Article GUID: 31002878
Dissociable mesolimbic dopamine circuits control responding triggered by alcohol-predictive discrete cues and contexts.

Author(s): Valyear MD, Glovaci I, Zaari A, Lahlou S, Trujillo-Pisanty I, Andrew Chapman C, Chaudhri N

Nat Commun. 2020 Jul 28;11(1):3764 Authors: Valyear MD, Glovaci I, Zaari A, Lahlou S, Trujillo-Pisanty I, Andrew Chapman C, Chaudhri N

Article GUID: 32724058
Comparing ABA, AAB, and ABC Renewal of Appetitive Pavlovian Conditioned Responding in Alcohol- and Sucrose-Trained Male Rats.

Author(s): Khoo SY, Sciascia JM, Brown A, Chaudhri N

Front Behav Neurosci. 2020;14:5 Authors: Khoo SY, Sciascia JM, Brown A, Chaudhri N

Article GUID: 32116588
Context controls the timing of responses to an alcohol-predictive conditioned stimulus.

Author(s): Valyear MD, Chaudhri N

Behav Processes. 2020 Feb 01;:104061 Authors: Valyear MD, Chaudhri N

Article GUID: 32017964
Considering Drug-Associated Contexts in Substance Use Disorders and Treatment Development.

Author(s): LeCocq MR, Randall PA, Besheer J, Chaudhri N

Neurotherapeutics. 2020 Jan 02;: Authors: LeCocq MR, Randall PA, Besheer J, Chaudhri N

Article GUID: 31898285
Alcohol-associated antecedent stimuli elicit alcohol seeking in non-dependent rats and may activate the insula.

Author(s): Cofresí RU, Grote DJ, Le EVT, Monfils MH, Chaudhri N, Gonzales RA, Lee HJ

Alcohol. 2019 May;76:91-102 Authors: Cofresí RU, Grote DJ, Le EVT, Monfils MH, Chaudhri N, Gonzales RA, Lee HJ

Article GUID: 30612041
The medial prefrontal cortex is required for responding to alcohol-predictive cues but only in the absence of alcohol delivery.

Author(s): Khoo SY, Sciascia JM, Pettorelli A, Maddux JN, Chaudhri N

J Psychopharmacol. 2019 May 09;:269881119844180 Authors: Khoo SY, Sciascia JM, Pettorelli A, Maddux JN, Chaudhri N

Article GUID: 31070082
Vendor differences in alcohol consumption and the contribution of dopamine receptors to Pavlovian-conditioned alcohol-seeking in Long-Evans rats.

Author(s): Sparks LM, Sciascia JM, Ayorech Z, Chaudhri N

Psychopharmacology (Berl). 2014 Feb;231(4):753-64 Authors: Sparks LM, Sciascia JM, Ayorech Z, Chaudhri N

Article GUID: 24096535
The attribution of incentive salience to Pavlovian alcohol cues: a shift from goal-tracking to sign-tracking.

Author(s): Srey CS, Maddux JM, Chaudhri N

Front Behav Neurosci. 2015;9:54 Authors: Srey CS, Maddux JM, Chaudhri N

Article GUID: 25784867
Alcohol-Seeking Triggered by Discrete Pavlovian Cues is Invigorated by Alcohol Contexts and Mediated by Glutamate Signaling in the Basolateral Amygdala.

Author(s): Sciascia JM, Reese RM, Janak PH, Chaudhri N

Neuropsychopharmacology. 2015 Nov;40(12):2801-12 Authors: Sciascia JM, Reese RM, Janak PH, Chaudhri N

Article GUID: 25953360
Robust optical fiber patch-cords for in vivo optogenetic experiments in rats.

Author(s): Trujillo-Pisanty I, Sanio C, Chaudhri N, Shizgal P

MethodsX. 2015;2:263-71 Authors: Trujillo-Pisanty I, Sanio C, Chaudhri N, Shizgal P

Article GUID: 26150997
Varenicline Reduces Context-Induced Relapse to Alcohol-Seeking through Actions in the Nucleus Accumbens.

Author(s): Lacroix F, Pettorelli A, Maddux JN, Heidari-Jam A, Chaudhri N

Neuropsychopharmacology. 2017 Apr;42(5):1037-1048 Authors: Lacroix F, Pettorelli A, Maddux JN, Heidari-Jam A, Chaudhri N

Article GUID: 27834390
Nicotine-induced enhancement of Pavlovian alcohol-seeking behavior in rats.

Author(s): Maddux JN, Chaudhri N

Psychopharmacology (Berl). 2017 Feb;234(4):727-738 Authors: Maddux JN, Chaudhri N

Article GUID: 28011981
Individual Differences in the Attribution of Incentive Salience to a Pavlovian Alcohol Cue.

Author(s): Villaruel FR, Chaudhri N

Front Behav Neurosci. 2016;10:238 Authors: Villaruel FR, Chaudhri N

Article GUID: 28082877
Postretrieval Extinction Attenuates Alcohol Cue Reactivity in Rats.

Author(s): Cofresí RU, Lewis SM, Chaudhri N, Lee HJ, Monfils MH, Gonzales RA

Alcohol Clin Exp Res. 2017 03;41(3):608-617 Authors: Cofresí RU, Lewis SM, Chaudhri N, Lee HJ, Monfils MH, Gonzales RA

Article GUID: 28169439
Alcohol-seeking and relapse: A focus on incentive salience and contextual conditioning.

Author(s): Valyear MD, Villaruel FR, Chaudhri N

Behav Processes. 2017 Aug;141(Pt 1):26-32 Authors: Valyear MD, Villaruel FR, Chaudhri N

Article GUID: 28473252
Optogenetic Activation of the Infralimbic Cortex Suppresses the Return of Appetitive Pavlovian-Conditioned Responding Following Extinction.

Author(s): Villaruel FR, Lacroix F, Sanio C, Sparks DW, Chapman CA, Chaudhri N

Cereb Cortex. 2018 Dec 01;28(12):4210-4221 Authors: Villaruel FR, Lacroix F, Sanio C, Sparks DW, Chapman CA, Chaudhri N

Article GUID: 29045570
Characterizing conditioned reactivity to sequential alcohol-predictive cues in well-trained rats.

Author(s): Cofresí RU, Lee HJ, Monfils MH, Chaudhri N, Gonzales RA

Alcohol. 2018 Jun;69:41-49 Authors: Cofresí RU, Lee HJ, Monfils MH, Chaudhri N, Gonzales RA

Article GUID: 29635111
Modeling Relapse to Pavlovian Alcohol-Seeking in Rats Using Reinstatement and Spontaneous Recovery Paradigms.

Author(s): LeCocq MR, Lahlou S, Chahine M, Padillo LN, Chaudhri N

Alcohol Clin Exp Res. 2018 Sep;42(9):1795-1806 Authors: LeCocq MR, Lahlou S, Chahine M, Padillo LN, Chaudhri N

Article GUID: 29969151
Context and topography determine the role of basolateral amygdala metabotropic glutamate receptor 5 in appetitive Pavlovian responding.

Author(s): Khoo SY, LeCocq MR, Deyab GE, Chaudhri N

Neuropsychopharmacology. 2019 Feb 08;: Authors: Khoo SY, LeCocq MR, Deyab GE, Chaudhri N

Article GUID: 30758331
Title:The attribution of incentive salience to Pavlovian alcohol cues: a shift from goal-tracking to sign-tracking.
Authors:Srey CS,  Maddux JM,  Chaudhri N
Link:https://www.ncbi.nlm.nih.gov/pubmed/25784867?dopt=Abstract
Category:Front Behav Neurosci
PMID:25784867
Dept Affiliation: CSBN
1 Department of Psychology, Center for Studies in Behavioral Neurobiology/FRQS Groupe de Recherche en Neurobiologie Comportementale, Concordia University Montreal, QC, Canada.

Description:

The attribution of incentive salience to Pavlovian alcohol cues: a shift from goal-tracking to sign-tracking.

Front Behav Neurosci. 2015;9:54

Authors: Srey CS, Maddux JM, Chaudhri N

Abstract

Environmental stimuli that are reliably paired with alcohol may acquire incentive salience, a property that can operate in the use and abuse of alcohol. Here we investigated the incentive salience of Pavlovian alcohol cues using a preclinical animal model. Male, Long-Evans rats (Harlan) with unrestricted access to food and water were acclimated to drinking 15% ethanol (v/v) in their home-cages. Rats then received Pavlovian autoshaping training in which the 10 s presentation of a retractable lever served as the conditioned stimulus (CS) and 15% ethanol served as the unconditioned stimulus (US) (0.2 ml/CS; 12 CS presentations/session; 27 sessions). Next, in an operant test of conditioned reinforcement, nose pokes into an active aperture delivered presentations of the lever-CS, whereas nose pokes into an inactive aperture had no consequences. Across initial autoshaping sessions, goal-tracking behavior, as measured by entries into the fluid port where ethanol was delivered, developed rapidly. However, with extended training goal-tracking diminished, and sign-tracking responses, as measured by lever-CS activations, emerged. Control rats that received explicitly unpaired CS and US presentations did not show goal-tracking or sign-tracking responses. In the test for conditioned reinforcement, rats with CS-US pairings during autoshaping training made more active relative to inactive nose pokes, whereas rats in the unpaired control group did not. Moreover, active nose pokes were positively correlated with sign-tracking behavior during autoshaping. Extended training may produce a shift in the learned properties of Pavlovian alcohol cues, such that after initially predicting alcohol availability they acquire robust incentive salience.

PMID: 25784867 [PubMed]