Keyword search (3,168 papers available)


BOLD signal physiology: Models and applications.

Author(s): Gauthier CJ, Fan AP

Neuroimage. 2019 02 15;187:116-127 Authors: Gauthier CJ, Fan AP

Article GUID: 29544818
High resolution atlas of the venous brain vasculature from 7 T quantitative susceptibility maps.

Author(s): Huck J, Wanner Y, Fan AP, Jäger AT, Grahl S, Schneider U, Villringer A, Steele CJ, Tardif CL, Bazin PL, Gauthier CJ

Brain Struct Funct. 2019 Jul 05;: Authors: Huck J, Wanner Y, Fan AP, Jäger AT, Grahl S, Schneider U, Villringer A, Steele CJ, Tardif CL, Bazin PL, Gauthier CJ

Article GUID: 31278570
Higher cardiovascular fitness level is associated with lower cerebrovascular reactivity and perfusion in healthy older adults.

Author(s): Intzandt B, Sabra D, Foster C, Desjardins-Crépeau L, Hoge RD, Steele CJ, Bherer L, Gauthier CJ

J Cereb Blood Flow Metab. 2019 Jul 25;:271678X19862873 Authors: Intzandt B, Sabra D, Foster C, Desjardins-Crépeau L, Hoge RD, Steele CJ, Bherer L, Gauthier CJ

Article GUID: 31342831
Advanced MRI techniques to improve our understanding of experience-induced neuroplasticity.

Author(s): Tardif CL, Gauthier CJ, Steele CJ, Bazin PL, Schäfer A, Schaefer A, Turner R, Villringer A

Neuroimage. 2016 05 01;131:55-72 Authors: Tardif CL, Gauthier CJ, Steele CJ, Bazin PL, Schäfer A, Schaefer A, Turner R, Villringer A

Article GUID: 26318050
Elevated brain oxygen extraction fraction measured by MRI susceptibility relates to perfusion status in acute ischemic stroke.

Author(s): Fan AP, Khalil AA, Fiebach JB, Zaharchuk G, Villringer A, Villringer K, Gauthier CJ

J Cereb Blood Flow Metab. 2019 Feb 07;:271678X19827944 Authors: Fan AP, Khalil AA, Fiebach JB, Zaharchuk G, Villringer A, Villringer K, Gauthier CJ

Article GUID: 30732551
Arterial stiffness and brain integrity: A review of MRI findings.

Author(s): Badji A, Sabra D, Bherer L, Cohen-Adad J, Girouard H, Gauthier CJ

Ageing Res Rev. 2019 May 04;53:100907 Authors: Badji A, Sabra D, Bherer L, Cohen-Adad J, Girouard H, Gauthier CJ

Article GUID: 31063866
Higher levels of cardiovascular fitness are associated with better executive function and prefrontal oxygenation in younger and older women.

Author(s): Dupuy O, Gauthier CJ, Fraser SA, Desjardins-Crèpeau L, Desjardins M, Mekary S, Lesage F, Hoge RD, Pouliot P, Bherer L

Front Hum Neurosci. 2015;9:66 Authors: Dupuy O, Gauthier CJ, Fraser SA, Desjardins-Crèpeau L, Desjardins M, Mekary S, Lesage F, Hoge RD, Pouliot P, Bherer L

Article GUID: 25741267
Investigation of the confounding effects of vasculature and metabolism on computational anatomy studies.

Author(s): Tardif CL, Steele CJ, Lampe L, Bazin PL, Ragert P, Villringer A, Gauthier CJ

Neuroimage. 2017 04 01;149:233-243 Authors: Tardif CL, Steele CJ, Lampe L, Bazin PL, Ragert P, Villringer A, Gauthier CJ

Article GUID: 28159689
Age differences in brain signal variability are robust to multiple vascular controls.

Author(s): Garrett DD, Lindenberger U, Hoge RD, Gauthier CJ

Sci Rep. 2017 08 31;7(1):10149 Authors: Garrett DD, Lindenberger U, Hoge RD, Gauthier CJ

Article GUID: 28860455
Title:BOLD signal physiology: Models and applications.
Authors:Gauthier CJ,  Fan AP
Link:https://www.ncbi.nlm.nih.gov/pubmed/29544818?dopt=Abstract
Category:Neuroimage
PMID:29544818
Dept Affiliation: IMAGING
1 Concordia University, Montreal, Canada. Electronic address: claudine.gauthier@concordia.ca.
2 Stanford University, California, USA.

Description:

BOLD signal physiology: Models and applications.

Neuroimage. 2019 02 15;187:116-127

Authors: Gauthier CJ, Fan AP

Abstract

The BOLD contrast mechanism has a complex relationship with functional brain activity, oxygen metabolism, and neurovascular factors. Accurate interpretation of the BOLD signal for neuroscience and clinical applications necessitates a clear understanding of the sources of BOLD contrast and its relationship to underlying physiology. This review describes the physiological components that contribute to the BOLD signal and the steady-state calibrated BOLD models that enable quantification of functional changes with a separate challenge paradigm. The principles derived from these biophysical models are then used to interpret BOLD measurements in different neurological disorders in the presence of confounding vascular factors related to disease.

PMID: 29544818 [PubMed - indexed for MEDLINE]