Keyword search (3,619 papers available)


Functional PVDF ultrafiltration membrane for Tetrabromobisphenol-A (TBBPA) removal with high water recovery.

Author(s): Chen X, Huang G, Li Y, An C, Feng R, Wu Y, Shen J

Water Res. 2020 May 18;181:115952 Authors: Chen X, Huang G, Li Y, An C, Feng R, Wu Y, Shen J

Article GUID: 32497754
Effect of dissolved oxygen on simultaneous removal of ammonia, nitrate and phosphorus via biological aerated filter with sulfur and pyrite as composite fillers.

Author(s): Li Y, Guo J, Li H, Song Y, Chen Z, Lu C, Han Y, Hou Y

Bioresour Technol. 2019 Oct 28;296:122340 Authors: Li Y, Guo J, Li H, Song Y, Chen Z, Lu C, Han Y, Hou Y

Article GUID: 31704601
Resting-state and Vocabulary Tasks Distinctively Inform On Age-Related Differences in the Functional Brain Connectome.

Author(s): Ferré P, Benhajali Y, Steffener J, Stern Y, Joanette Y, Bellec P

Resting-state and Vocabulary Tasks Distinctively Inform On Age-Related Differences in the Functional Brain Connectome.
Lang Cogn Neurosci. 2019;34(8):949-972
Authors: Ferré P, Benhajali Y, Steffener J, Stern Y, Joanette Y, Bellec P
Abstract
...

Article GUID: 31457069
Chemogenomic Profiling of the Fungal Pathogen Candida albicans.

Author(s): Chen Y, Mallick J, Maqnas A, Sun Y, Choudhury BI, Côte P, Yan L, Ni TJ, Li Y, Zhang D, Rodríguez-Ortiz R, Lv QZ, Jiang YY, Whiteway M

Antimicrob Agents Chemother. 2018 02;62(2): Authors: Chen Y, Mallick J, Maqnas A, Sun Y, Choudhury BI, Côte P, Yan L, Ni TJ, Li Y, Zhang D, Rodríguez-Ortiz R, Lv QZ, Jiang YY, Whiteway M

Article GUID: 29203491
Erratum for Chen et al., "Chemogenomic Profiling of the Fungal Pathogen Candida albicans".

Author(s): Chen Y, Mallick J, Maqnas A, Sun Y, Choudhury BI, Côte P, Yan L, Ni TJ, Li Y, Zhang D, Rodríguez-Ortiz R, Lv QZ, Jiang YY, Whiteway M...

Antimicrob Agents Chemother. 2018 04;62(4): Authors: Chen Y, Mallick J, Maqnas A, Sun Y, Choudhury BI, Côte P, Yan L, Ni TJ, Li Y, Zhang D, Rodríguez-Ortiz R, Lv QZ, Jiang YY, Whiteway M...

Article GUID: 29588354
A Highly Effective Component Vaccine against Nontyphoidal Salmonella enterica Infections.

Author(s): Ferreira RB, Valdez Y, Coombes BK, Sad S, Gouw JW, Brown EM, Li Y, Grassl GA, Antunes LC, Gill N, Truong M, Scholz R, Reynolds LA, Krishnan ...

MBio. 2015 Sep 22;6(5):e01421-15 Authors: Ferreira RB, Valdez Y, Coombes BK, Sad S, Gouw JW, Brown EM, Li Y, Grassl GA, Antunes LC, Gill N, Truong M, Scholz R, Reynolds LA, Krishnan L, Zafer AA, S...

Article GUID: 26396246
MEG-EEG Information Fusion and Electromagnetic Source Imaging: From Theory to Clinical Application in Epilepsy.

Author(s): Chowdhury RA, Zerouali Y, Hedrich T, Heers M, Kobayashi E, Lina JM, Grova C

Brain Topogr. 2015 Nov;28(6):785-812 Authors: Chowdhury RA, Zerouali Y, Hedrich T, Heers M, Kobayashi E, Lina JM, Grova C

Article GUID: 26016950
The role of change in self-criticism across young adulthood in explaining developmental outcomes and psychological wellbeing.

Author(s): Michaeli Y, Kalfon Hakhmigari M, Dickson DJ, Scharf M, Shulman S

J Pers. 2018 Sep 27;: Authors: Michaeli Y, Kalfon Hakhmigari M, Dickson DJ, Scharf M, Shulman S

Article GUID: 30260502
Intracellular Delivery of Colloidally Stable Core-Cross-Linked Triblock Copolymer Micelles with Glutathione-Responsive Enhanced Drug Release for Cancer Therapy.

Author(s): Biswas D, An SY, Li Y, Wang X, Oh JK

Mol Pharm. 2017 08 07;14(8):2518-2528 Authors: Biswas D, An SY, Li Y, Wang X, Oh JK

Article GUID: 28207270
Title:Intracellular Delivery of Colloidally Stable Core-Cross-Linked Triblock Copolymer Micelles with Glutathione-Responsive Enhanced Drug Release for Cancer Therapy.
Authors:Biswas D,  An SY,  Li Y,  Wang X,  Oh JK
Link:https://www.ncbi.nlm.nih.gov/pubmed/28207270?dopt=Abstract
Category:Mol Pharm
PMID:28207270
Dept Affiliation: CHEMBIOCHEM
1 Department of Chemistry and Biochemistry, Concordia University , Montreal, Quebec Canada H4B 1R6.
2 Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College , No. 151, Malianwa North Road, Haidian District, Beijing 100193, China.

Description:

Intracellular Delivery of Colloidally Stable Core-Cross-Linked Triblock Copolymer Micelles with Glutathione-Responsive Enhanced Drug Release for Cancer Therapy.

Mol Pharm. 2017 08 07;14(8):2518-2528

Authors: Biswas D, An SY, Li Y, Wang X, Oh JK

Abstract

Design and development of amphiphilic block copolymer-based nanocarriers exhibiting enhanced colloidal stability upon dilution in the blood and cellular glutathione-responsive rapid drug release is highly desired for tumor-targeting chemotherapy. Herein, we report a novel ABA-type triblock copolymer consisting of a hydrophilic central poly(ethylene glycol) block and two terminal hydrophobic blocks of a polymethacrylate having pendant disulfides (PHMssEt), thus PHMssEt-b-PEG-b-PHMssEt (ssTP). Aqueous self-assembly and the following disulfide-exchange reaction of the resulting ssTP allow for formation of core-cross-linked micelles (CCMs) through the formation of new disulfide linkages, retaining enhanced colloidal stability in physiological conditions and in the presence of proteins. Further, they exhibit reduction-responsive enhanced release of encapsulated drugs in response to cellular concentrations of glutathione in cancer cells, confirmed by dynamic light scattering and spectroscopic analysis. Combined with these results, in vitro (cells) and in vivo (mouse model) biological results suggest that ssTP-based CCMs are effective candidates as intracellular nanocarriers targeting tumors for cancer therapy.

PMID: 28207270 [PubMed - indexed for MEDLINE]