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Interpersonal functioning in adolescent offspring of parents with bipolar disorder.

Author(s): Linnen AM, aan het Rot M, Ellenbogen MA, Young SN

J Affect Disord. 2009 Apr;114(1-3):122-30 Authors: Linnen AM, aan het Rot M, Ellenbogen MA, Young SN

Article GUID: 18692905
Chronic stress and stressful life events in the offspring of parents with bipolar disorder.

Author(s): Ostiguy CS, Ellenbogen MA, Linnen AM, Walker EF, Hammen C, Hodgins S

J Affect Disord. 2009 Apr;114(1-3):74-84 Authors: Ostiguy CS, Ellenbogen MA, Linnen AM, Walker EF, Hammen C, Hodgins S

Article GUID: 18814916
High cortisol levels in the offspring of parents with bipolar disorder during two weeks of daily sampling.

Author(s): Ellenbogen MA, Santo JB, Linnen AM, Walker CD, Hodgins S

Bipolar Disord. 2010 Feb;12(1):77-86 Authors: Ellenbogen MA, Santo JB, Linnen AM, Walker CD, Hodgins S

Article GUID: 20148869
Elevated daytime cortisol levels: a biomarker of subsequent major affective disorder?

Author(s): Ellenbogen MA, Hodgins S, Linnen AM, Ostiguy CS

J Affect Disord. 2011 Jul;132(1-2):265-9 Authors: Ellenbogen MA, Hodgins S, Linnen AM, Ostiguy CS

Article GUID: 21329985
Acute intranasal oxytocin improves positive self-perceptions of personality.

Author(s): Cardoso C, Ellenbogen MA, Linnen AM

Psychopharmacology (Berl). 2012 Apr;220(4):741-9 Authors: Cardoso C, Ellenbogen MA, Linnen AM

Article GUID: 22012170
Intranasal oxytocin and salivary cortisol concentrations during social rejection in university students.

Author(s): Linnen AM, Ellenbogen MA, Cardoso C, Joober R

Stress. 2012 Jul;15(4):393-402 Authors: Linnen AM, Ellenbogen MA, Cardoso C, Joober R

Article GUID: 22044077
The acute effects of intranasal oxytocin on automatic and effortful attentional shifting to emotional faces.

Author(s): Ellenbogen MA, Linnen AM, Grumet R, Cardoso C, Joober R

Psychophysiology. 2012 Jan;49(1):128-37 Authors: Ellenbogen MA, Linnen AM, Grumet R, Cardoso C, Joober R

Article GUID: 22092248
Intranasal oxytocin impedes the ability to ignore task-irrelevant facial expressions of sadness in students with depressive symptoms.

Author(s): Ellenbogen MA, Linnen AM, Cardoso C, Joober R

Psychoneuroendocrinology. 2013 Mar;38(3):387-98 Authors: Ellenbogen MA, Linnen AM, Cardoso C, Joober R

Article GUID: 22902063
Salivary cortisol and interpersonal functioning: an event-contingent recording study in the offspring of parents with bipolar disorder.

Author(s): Ellenbogen MA, Linnen AM, Santo JB, aan het Rot M, Hodgins S, Young SN

Psychoneuroendocrinology. 2013 Jul;38(7):997-1006 Authors: Ellenbogen MA, Linnen AM, Santo JB, aan het Rot M, Hodgins S, Young SN

Article GUID: 23131593
Stress-induced negative mood moderates the relation between oxytocin administration and trust: evidence for the tend-and-befriend response to stress?

Author(s): Cardoso C, Ellenbogen MA, Serravalle L, Linnen AM

Psychoneuroendocrinology. 2013 Nov;38(11):2800-4 Authors: Cardoso C, Ellenbogen MA, Serravalle L, Linnen AM

Article GUID: 23768973
Intranasal oxytocin attenuates the human acoustic startle response independent of emotional modulation.

Author(s): Ellenbogen MA, Linnen AM, Cardoso C, Joober R

Psychophysiology. 2014 Nov;51(11):1169-77 Authors: Ellenbogen MA, Linnen AM, Cardoso C, Joober R

Article GUID: 25082371
Title:Interpersonal functioning in adolescent offspring of parents with bipolar disorder.
Authors:Linnen AM,  aan het Rot M,  Ellenbogen MA,  Young SN
Link:https://www.ncbi.nlm.nih.gov/pubmed/18692905?dopt=Abstract
Category:J Affect Disord
PMID:18692905
Dept Affiliation: CRDH
1 Centre for Research in Human Development, Concordia University, Montréal (Québec), Canada.

Description:

Interpersonal functioning in adolescent offspring of parents with bipolar disorder.

J Affect Disord. 2009 Apr;114(1-3):122-30

Authors: Linnen AM, aan het Rot M, Ellenbogen MA, Young SN

Abstract

BACKGROUND: Poor interpersonal functioning may represent a putative prodromal feature of major affective disorder. However, no studies have examined the naturalistic patterns of social behaviours among the offspring of parents with a major affective disorder. The present study assessed daily social interactions among 25 offspring of parents with bipolar disorder and 23 control participants in late adolescence and young adulthood.

METHODS: Using event-contingent recording procedures, interpersonal behaviours and perceptions were assessed along four scales (quarrelsomeness, agreeableness, dominance, and submissiveness) and were measured during specific social interactions over 14 days.

RESULTS: Multilevel modeling analyses revealed no group differences on any of the four scales, but gender by group interactions were was observed. High-risk males reported higher mean levels of quarrelsome behaviour and lower mean levels of agreeable behaviour than high-risk females, whereas low-risk males and females reported comparable levels of affiliative behaviours. High-risk participants reported more externalizing, but not internalizing, problems on the Achenbach Youth Self-Report Form than low-risk participants.

LIMITATIONS: Although event-contingent recording reduces the self-report bias associated with self-report questionnaires, participants may have been biased in the selection of interactions they chose to record.

CONCLUSIONS: Overall, the offspring of parents with BD, relative to controls, report no deficits in social functioning in the natural environment. However, high-risk youth displayed elevated externalizing problems and gender-specific patterns of social functioning that may precede the development of major affective disorder.

PMID: 18692905 [PubMed - indexed for MEDLINE]