Keyword search (3,619 papers available)


The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4.

Author(s): Pathak SS, Liu D, Li T, de Zavalia N, Zhu L, Li J, Karthikeyan R, Alain T, Liu AC, Storch KF, Kaufman RJ, Jin VX, Amir S, Sonenberg N, Cao R

Neuron. 2019 Aug 26;: Authors: Pathak SS, Liu D, Li T, de Zavalia N, Zhu L, Li J, Karthikeyan R, Alain T, Liu AC, Storch KF, Kaufman RJ, Jin VX, Amir S, Sonenberg N, Cao R

Article GUID: 31522764
Effects of bilateral anterior agranular insula lesions on food anticipatory activity in rats.

Author(s): Gavrila AM, Hood S, Robinson B, Amir S

PLoS One. 2017;12(6):e0179370 Authors: Gavrila AM, Hood S, Robinson B, Amir S

Article GUID: 28594962
Circadian Rhythms in Regulation of Brain Processes and Role in Psychiatric Disorders.

Author(s): Pantazopoulos H, Gamble K, Stork O, Amir S

Neural Plast. 2018;2018:5892657 Authors: Pantazopoulos H, Gamble K, Stork O, Amir S PMID: 29887881 [PubMed - indexed for MEDLINE]

Article GUID: 29887881
Mapping the co-localization of the circadian proteins PER2 and BMAL1 with enkephalin and substance P throughout the rodent forebrain.

Author(s): Frederick A, Goldsmith J, de Zavalia N, Amir S

PLoS One. 2017;12(4):e0176279 Authors: Frederick A, Goldsmith J, de Zavalia N, Amir S

Article GUID: 28423013
Comprehensive mapping of regional expression of the clock protein PERIOD2 in rat forebrain across the 24-h day.

Author(s): Harbour VL, Weigl Y, Robinson B, Amir S

PLoS One. 2013;8(10):e76391 Authors: Harbour VL, Weigl Y, Robinson B, Amir S

Article GUID: 24124556
Phase differences in expression of circadian clock genes in the central nucleus of the amygdala, dentate gyrus, and suprachiasmatic nucleus in the rat.

Author(s): Harbour VL, Weigl Y, Robinson B, Amir S

PLoS One. 2014;9(7):e103309 Authors: Harbour VL, Weigl Y, Robinson B, Amir S

Article GUID: 25068868
Diurnal influences on electrophysiological oscillations and coupling in the dorsal striatum and cerebellar cortex of the anesthetized rat.

Author(s): Frederick A, Bourget-Murray J, Chapman CA, Amir S, Courtemanche R

Front Syst Neurosci. 2014;8:145 Authors: Frederick A, Bourget-Murray J, Chapman CA, Amir S, Courtemanche R

Article GUID: 25309348
Stress-induced changes in the expression of the clock protein PERIOD1 in the rat limbic forebrain and hypothalamus: role of stress type, time of day, and predictability.

Author(s): Al-Safadi S, Al-Safadi A, Branchaud M, Rutherford S, Dayanandan A, Robinson B, Amir S

PLoS One. 2014;9(10):e111166 Authors: Al-Safadi S, Al-Safadi A, Branchaud M, Rutherford S, Dayanandan A, Robinson B, Amir S

Article GUID: 25338089
Light-regulated translational control of circadian behavior by eIF4E phosphorylation.

Author(s): Cao R, Gkogkas CG, de Zavalia N, Blum ID, Yanagiya A, Tsukumo Y, Xu H, Lee C, Storch KF, Liu AC, Amir S, Sonenberg N

Nat Neurosci. 2015 Jun;18(6):855-62 Authors: Cao R, Gkogkas CG, de Zavalia N, Blum ID, Yanagiya A, Tsukumo Y, Xu H, Lee C, Storch KF, Liu AC, Amir S, Sonenberg N

Article GUID: 25915475
Glucocorticoids and Stress-Induced Changes in the Expression of PERIOD1 in the Rat Forebrain.

Author(s): Al-Safadi S, Branchaud M, Rutherford S, Amir S

PLoS One. 2015;10(6):e0130085 Authors: Al-Safadi S, Branchaud M, Rutherford S, Amir S

Article GUID: 26075608
Circadian Rhythms and Psychopathology: From Models of Depression to Rhythms in Clock Gene Expression and Back Again.

Author(s): Verwey M, Al-Safadi S, Amir S

Biol Psychiatry. 2015 Aug 15;78(4):220-1 Authors: Verwey M, Al-Safadi S, Amir S PMID: 26195175 [PubMed - indexed for MEDLINE]

Article GUID: 26195175
From genes to chronotypes: the influence of circadian clock genes on our daily patterns of sleep and wakefulness.

Author(s): Verwey M, Amir S

Ann Transl Med. 2016 May;4(9):184 Authors: Verwey M, Amir S PMID: 27275497 [PubMed]

Article GUID: 27275497
Exploring the role of locomotor sensitization in the circadian food entrainment pathway.

Author(s): Opiol H, de Zavalia N, Delorme T, Solis P, Rutherford S, Shalev U, Amir S

PLoS One. 2017;12(3):e0174113 Authors: Opiol H, de Zavalia N, Delorme T, Solis P, Rutherford S, Shalev U, Amir S

Article GUID: 28301599
Individual differences in circadian locomotor parameters correlate with anxiety- and depression-like behavior.

Author(s): Anyan J, Verwey M, Amir S

PLoS One. 2017;12(8):e0181375 Authors: Anyan J, Verwey M, Amir S

Article GUID: 28763478
Too Depressed to Swim or Too Afraid to Stop? A Reinterpretation of the Forced Swim Test as a Measure of Anxiety-Like Behavior.

Author(s): Anyan J, Amir S

Neuropsychopharmacology. 2018 04;43(5):931-933 Authors: Anyan J, Amir S PMID: 29210364 [PubMed - in process]

Article GUID: 29210364
Title:Diurnal influences on electrophysiological oscillations and coupling in the dorsal striatum and cerebellar cortex of the anesthetized rat.
Authors:Frederick A,  Bourget-Murray J,  Chapman CA,  Amir S,  Courtemanche R
Link:https://www.ncbi.nlm.nih.gov/pubmed/25309348?dopt=Abstract
Category:Front Syst Neurosci
PMID:25309348
Dept Affiliation: BIOLOGY
1 Center for Studies in Behavioral Neurobiology/FRQS Groupe de Recherche en Neurobiologie Comportementale, Concordia University Montreal, QC, Canada ; Department of Biology, Concordia University Montreal, QC, Canada.
2 Center for Studies in Behavioral Neurobiology/FRQS Groupe de Recherche en Neurobiologie Comportementale, Concordia University Montreal, QC, Canada ; M.D., C.M. Program, Faculty of Medicine, McGill University Montreal, QC, Canada.
3 Center for Studies in Behavioral Neurobiology/FRQS Groupe de Recherche en Neurobiologie Comportementale, Concordia University Montreal, QC, Canada ; Department of Psychology, Concordia University Montreal, QC, Canada.
4 Center for Studies in Behavioral Neurobiology/FRQS Groupe de Recherche en Neurobiologie Comportementale, Concordia University Montreal, QC, Canada ; Department of Exercise Science, Concordia University Montreal, QC, Canada.

Description:

Diurnal influences on electrophysiological oscillations and coupling in the dorsal striatum and cerebellar cortex of the anesthetized rat.

Front Syst Neurosci. 2014;8:145

Authors: Frederick A, Bourget-Murray J, Chapman CA, Amir S, Courtemanche R

Abstract

Circadian rhythms modulate behavioral processes over a 24 h period through clock gene expression. What is largely unknown is how these molecular influences shape neural activity in different brain areas. The clock gene Per2 is rhythmically expressed in the striatum and the cerebellum and its expression is linked with daily fluctuations in extracellular dopamine levels and D2 receptor activity. Electrophysiologically, dopamine depletion enhances striatal local field potential (LFP) oscillations. We investigated if LFP oscillations and synchrony were influenced by time of day, potentially via dopamine mechanisms. To assess the presence of a diurnal effect, oscillatory power and coherence were examined in the striatum and cerebellum of rats under urethane anesthesia at four different times of day zeitgeber time (ZT1, 7, 13 and 19-indicating number of hours after lights turned on in a 12:12 h light-dark cycle). We also investigated the diurnal response to systemic raclopride, a D2 receptor antagonist. Time of day affected the proportion of LFP oscillations within the 0-3 Hz band and the 3-8 Hz band. In both the striatum and the cerebellum, slow oscillations were strongest at ZT1 and weakest at ZT13. A 3-8 Hz oscillation was present when the slow oscillation was lowest, with peak 3-8 Hz activity occurring at ZT13. Raclopride enhanced the slow oscillations, and had the greatest effect at ZT13. Within the striatum and with the cerebellum, 0-3 Hz coherence was greatest at ZT1, when the slow oscillations were strongest. Coherence was also affected the most by raclopride at ZT13. Our results suggest that neural oscillations in the cerebellum and striatum, and the synchrony between these areas, are modulated by time of day, and that these changes are influenced by dopamine manipulation. This may provide insight into how circadian gene transcription patterns influence network electrophysiology. Future experiments will address how these network alterations are linked with behavior.

PMID: 25309348 [PubMed]