Keyword search (3,619 papers available)


Fast oscillations >40 Hz localize the epileptogenic zone: An electrical source imaging study using high-density electroencephalography.

Author(s): Avigdor T, Abdallah C, von Ellenrieder N, Hedrich T, Rubino A, Lo Russo G, Bernhardt B, Nobili L, Grova C, Frauscher B...

OBJECTIVE: Fast Oscillations (FO) >40 Hz are a promising biomarker of the epileptogenic zone (EZ). Evidence using scalp electroencephalography (EEG) remains scarce. We assessed if electrical source...

Article GUID: 33450578

Contactless Capacitive Electrocardiography Using Hybrid Flexible Printed Electrodes.

Author(s): Lessard-Tremblay M, Weeks J, Morelli L, Cowan G, Gagnon G, Zednik RJ

Traditional capacitive electrocardiogram (cECG) electrodes suffer from limited patient comfort, difficulty of disinfection and low signal-to-noise ratio in addition to the challenge of integrating them in wearables. A novel hybrid flexible cECG electrode wa...

Article GUID: 32927651

The antibacterial activity of p-tert-butylcalix[6]arene and its effect on a membrane model: molecular dynamics and Langmuir film studies.

Author(s): Wrobel EC, de Lara LS, do Carmo TAS, Castellen P, Lazzarotto M, de Lázaro SR, Camilo A, Caseli L, Schmidt R, DeWolf CE, Wohnrath K

Phys Chem Chem Phys. 2020 Mar 03;: Authors: Wrobel EC, de Lara LS, do Carmo TAS, Castellen P, Lazzarotto M, de Lázaro SR, Camilo A, Caseli L, Schmidt R, DeWolf CE, Wohnrath K

Article GUID: 32124897

Computer-Aided Diagnosis System of Alzheimer's Disease Based on Multimodal Fusion: Tissue Quantification Based on the Hybrid Fuzzy-Genetic-Possibilistic Model and Discriminative Classification Based on the SVDD Model.

Author(s): Lazli L, Boukadoum M, Ait Mohamed O

Brain Sci. 2019 Oct 22;9(10): Authors: Lazli L, Boukadoum M, Ait Mohamed O

Article GUID: 31652635

The first MICCAI challenge on PET tumor segmentation.

Author(s): Hatt M, Laurent B, Ouahabi A, Fayad H, Tan S, Li L, Lu W, Jaouen V, Tauber C, Czakon J, Drapejkowski F, Dyrka W, Camarasu-Pop S, Cervenansky...

Med Image Anal. 2018 02;44:177-195 Authors: Hatt M, Laurent B, Ouahabi A, Fayad H, Tan S, Li L, Lu W, Jaouen V, Tauber C, Czakon J, Drapejkowski F, Dyrka W, Camarasu-Pop S, Cervenansky F, Girard P...

Article GUID: 29268169

Caloric restriction extends yeast chronological lifespan via a mechanism linking cellular aging to cell cycle regulation, maintenance of a quiescent state, entry into a non-quiescent state and survival in the non-quiescent state.

Author(s): Leonov A, Feldman R, Piano A, Arlia-Ciommo A, Lutchman V, Ahmadi M, Elsaser S, Fakim H, Heshmati-Moghaddam M, Hussain A, Orfali S, Rajen H, ...

Oncotarget. 2017 Sep 19;8(41):69328-69350 Authors: Leonov A, Feldman R, Piano A, Arlia-Ciommo A, Lutchman V, Ahmadi M, Elsaser S, Fakim H, Heshmati-Moghaddam M, Hussain A, Orfali S, Rajen H, Roofi...

Article GUID: 29050207

Expedition Cognition: A Review and Prospective of Subterranean Neuroscience With Spaceflight Applications.

Author(s): Mogilever NB, Zuccarelli L, Burles F, Iaria G, Strapazzon G, Bessone L, Coffey EBJ

Front Hum Neurosci. 2018;12:407 Authors: Mogilever NB, Zuccarelli L, Burles F, Iaria G, Strapazzon G, Bessone L, Coffey EBJ

Article GUID: 30425628

Human Physiology During Exposure to the Cave Environment: A Systematic Review With Implications for Aerospace Medicine.

Author(s): Zuccarelli L, Galasso L, Turner R, Coffey EJB, Bessone L, Strapazzon G

Front Physiol. 2019;10:442 Authors: Zuccarelli L, Galasso L, Turner R, Coffey EJB, Bessone L, Strapazzon G

Article GUID: 31068833


Title:Caloric restriction extends yeast chronological lifespan via a mechanism linking cellular aging to cell cycle regulation, maintenance of a quiescent state, entry into a non-quiescent state and survival in the non-quiescent state.
Authors:Leonov AFeldman RPiano AArlia-Ciommo ALutchman VAhmadi MElsaser SFakim HHeshmati-Moghaddam MHussain AOrfali SRajen HRoofigari-Esfahani NRosanelli LTitorenko VI
Link:https://www.ncbi.nlm.nih.gov/pubmed/29050207?dopt=Abstract
DOI:10.18632/oncotarget.20614
Category:Oncotarget
PMID:29050207
Dept Affiliation: BIOLOGY
1 Department of Biology, Concordia University, Montreal, Quebec, Canada.

Description:

Caloric restriction extends yeast chronological lifespan via a mechanism linking cellular aging to cell cycle regulation, maintenance of a quiescent state, entry into a non-quiescent state and survival in the non-quiescent state.

Oncotarget. 2017 Sep 19;8(41):69328-69350

Authors: Leonov A, Feldman R, Piano A, Arlia-Ciommo A, Lutchman V, Ahmadi M, Elsaser S, Fakim H, Heshmati-Moghaddam M, Hussain A, Orfali S, Rajen H, Roofigari-Esfahani N, Rosanelli L, Titorenko VI

Abstract

A yeast culture grown in a nutrient-rich medium initially containing 2% glucose is not limited in calorie supply. When yeast cells cultured in this medium consume glucose, they undergo cell cycle arrest at a checkpoint in late G1 and differentiate into quiescent and non-quiescent cell populations. Studies of such differentiation have provided insights into mechanisms of yeast chronological aging under conditions of excessive calorie intake. Caloric restriction is an aging-delaying dietary intervention. Here, we assessed how caloric restriction influences the differentiation of chronologically aging yeast cultures into quiescent and non-quiescent cells, and how it affects their properties. We found that caloric restriction extends yeast chronological lifespan via a mechanism linking cellular aging to cell cycle regulation, maintenance of quiescence, entry into a non-quiescent state and survival in this state. Our findings suggest that caloric restriction delays yeast chronological aging by causing specific changes in the following: 1) a checkpoint in G1 for cell cycle arrest and entry into a quiescent state; 2) a growth phase in which high-density quiescent cells are committed to become low-density quiescent cells; 3) the differentiation of low-density quiescent cells into low-density non-quiescent cells; and 4) the conversion of high-density quiescent cells into high-density non-quiescent cells.

PMID: 29050207 [PubMed]