Keyword search (3,448 papers available)


Using intracellular plasmonics to characterize nanomorphology in human cells.

Author(s): Sohrabi Kashani A, Piekny A, Packirisamy M

Determining the characteristics and localization of nanoparticles inside cells is crucial for nanomedicine design for cancer therapy. Hyperspectral imaging is a fast, straightforward, reliable, and accurate method to study the interactions of nanoparticles ...

Article GUID: 33365137
Gold Nano-Island Platforms for Localized Surface Plasmon Resonance Sensing: A Short Review.

Author(s): Badilescu S, Raju D, Bathini S, Packirisamy M

Nano-islands are entities (droplets or other shapes) that are formed by spontaneous dewetting (agglomeration, in the early literature) of thin and very thin metallic (especially gold) films on a substrate, done by post-deposition heating or by using other s...

Article GUID: 33066088
Toward Task Autonomy in Robotic Cardiac Ablation: Learning-Based Kinematic Control of Soft Tendon-Driven Catheters.

Author(s): Jolaei M, Hooshiar A, Dargahi J, Packirisamy M

Soft Robot. 2020 Jul 14;: Authors: Jolaei M, Hooshiar A, Dargahi J, Packirisamy M

Article GUID: 32678722
Lab-On-A-Chip for the Development of Pro-/Anti-Angiogenic Nanomedicines to Treat Brain Diseases.

Author(s): Subramaniyan Parimalam S, Badilescu S, Sonenberg N, Bhat R, Packirisamy M

Int J Mol Sci. 2019 Dec 05;20(24): Authors: Subramaniyan Parimalam S, Badilescu S, Sonenberg N, Bhat R, Packirisamy M

Article GUID: 31817343
Nano-Bio Interactions of Extracellular Vesicles with Gold Nanoislands for Early Cancer Diagnosis.

Author(s): Bathini S, Raju D, Badilescu S, Kumar A, Ouellette RJ, Ghosh A, Packirisamy M

Res (Wash D C). 2018;2018:3917986 Authors: Bathini S, Raju D, Badilescu S, Kumar A, Ouellette RJ, Ghosh A, Packirisamy M

Article GUID: 31549028
Flow force augmented 3D suspended polymeric microfluidic (SPMF3 ) platform.

Author(s): Marzban M, Dargahi J, Packirisamy M

Electrophoresis. 2019 Feb;40(3):388-400 Authors: Marzban M, Dargahi J, Packirisamy M

Article GUID: 30025169
Tuning of Morphology and Stability of Gold Nanostars Through pH Adjustment.

Author(s): Kumar R, Badilescu S, Packirisamy M

J Nanosci Nanotechnol. 2019 Aug 01;19(8):4617-4622 Authors: Kumar R, Badilescu S, Packirisamy M

Article GUID: 30913757
Efficient Low Shear Flow-based Trapping of Biological Entities.

Author(s): Sohrabi Kashani A, Packirisamy M

Sci Rep. 2019 Apr 02;9(1):5511 Authors: Sohrabi Kashani A, Packirisamy M

Article GUID: 30940862
Acoustofluidic Micromixing Enabled Hybrid Integrated Colorimetric Sensing, for Rapid Point-of-Care Measurement of Salivary Potassium.

Author(s): Surendran V, Chiulli T, Manoharan S, Knisley S, Packirisamy M, Chandrasekaran A

Biosensors (Basel). 2019 May 28;9(2): Authors: Surendran V, Chiulli T, Manoharan S, Knisley S, Packirisamy M, Chandrasekaran A

Article GUID: 31141923
The effect of hydrogen nanobubbles on the morphology of gold-gelatin bionanocomposite films and their optical properties.

Author(s): Alsawafta M, Badilescu S, Truong VV, Packirisamy M

Nanotechnology. 2012 Feb 17;23(6):065305 Authors: Alsawafta M, Badilescu S, Truong VV, Packirisamy M

Article GUID: 22248640
Title:Acoustofluidic Micromixing Enabled Hybrid Integrated Colorimetric Sensing, for Rapid Point-of-Care Measurement of Salivary Potassium.
Authors:Surendran V,  Chiulli T,  Manoharan S,  Knisley S,  Packirisamy M,  Chandrasekaran A
Link:https://www.ncbi.nlm.nih.gov/pubmed/31141923?dopt=Abstract
Category:Biosensors (Basel)
PMID:31141923
Dept Affiliation: ENCS
1 Department of Chemical, Biological and Bio Engineering, North Carolina A & T State University, Greensboro, NC 27411, USA. vsurendran@aggies.ncat.edu.
2 Department of Chemical, Biological and Bio Engineering, North Carolina A & T State University, Greensboro, NC 27411, USA. tjchiulli@aggies.ncat.edu.
3 Department of Chemical, Biological and Bio Engineering, North Carolina A & T State University, Greensboro, NC 27411, USA. smanoharan@aggies.ncat.edu.
4 Department of Chemical, Biological and Bio Engineering, North Carolina A & T State University, Greensboro, NC 27411, USA. sbknisle@ncat.edu.
5 Department of Mechanical, Industrial and Aerospace Engineering, Concordia University, Montreal, QC H2L5C9, Canada. pmuthu@alcor.concordia.ca.
6 Department of Chemical, Biological and Bio Engineering, North Carolina A & T State University, Greensboro, NC 27411, USA. achandra@ncat.edu.

Description:

Acoustofluidic Micromixing Enabled Hybrid Integrated Colorimetric Sensing, for Rapid Point-of-Care Measurement of Salivary Potassium.

Biosensors (Basel). 2019 May 28;9(2):

Authors: Surendran V, Chiulli T, Manoharan S, Knisley S, Packirisamy M, Chandrasekaran A

Abstract

The integration of microfluidics with advanced biosensor technologies offers tremendous advantages such as smaller sample volume requirement and precise handling of samples and reagents, for developing affordable point-of-care testing methodologies that could be used in hospitals for monitoring patients. However, the success and popularity of point-of-care diagnosis lies with the generation of instantaneous and reliable results through in situ tests conducted in a painless, non-invasive manner. This work presents the development of a simple, hybrid integrated optical microfluidic biosensor for rapid detection of analytes in test samples. The proposed biosensor works on the principle of colorimetric optical absorption, wherein samples mixed with suitable chromogenic substrates induce a color change dependent upon the analyte concentration that could then be detected by the absorbance of light in its path length. This optical detection scheme has been hybrid integrated with an acoustofluidic micromixing unit to enable uniform mixing of fluids within the device. As a proof-of-concept, we have demonstrated the real-time application of our biosensor format for the detection of potassium in whole saliva samples. The results show that our lab-on-a-chip technology could provide a useful strategy in biomedical diagnoses for rapid analyte detection towards clinical point-of-care testing applications.

PMID: 31141923 [PubMed - in process]