Keyword search (3,448 papers available)


Using intracellular plasmonics to characterize nanomorphology in human cells.

Author(s): Sohrabi Kashani A, Piekny A, Packirisamy M

Determining the characteristics and localization of nanoparticles inside cells is crucial for nanomedicine design for cancer therapy. Hyperspectral imaging is a fast, straightforward, reliable, and accurate method to study the interactions of nanoparticles ...

Article GUID: 33365137
Gold Nano-Island Platforms for Localized Surface Plasmon Resonance Sensing: A Short Review.

Author(s): Badilescu S, Raju D, Bathini S, Packirisamy M

Nano-islands are entities (droplets or other shapes) that are formed by spontaneous dewetting (agglomeration, in the early literature) of thin and very thin metallic (especially gold) films on a substrate, done by post-deposition heating or by using other s...

Article GUID: 33066088
Toward Task Autonomy in Robotic Cardiac Ablation: Learning-Based Kinematic Control of Soft Tendon-Driven Catheters.

Author(s): Jolaei M, Hooshiar A, Dargahi J, Packirisamy M

Soft Robot. 2020 Jul 14;: Authors: Jolaei M, Hooshiar A, Dargahi J, Packirisamy M

Article GUID: 32678722
Lab-On-A-Chip for the Development of Pro-/Anti-Angiogenic Nanomedicines to Treat Brain Diseases.

Author(s): Subramaniyan Parimalam S, Badilescu S, Sonenberg N, Bhat R, Packirisamy M

Int J Mol Sci. 2019 Dec 05;20(24): Authors: Subramaniyan Parimalam S, Badilescu S, Sonenberg N, Bhat R, Packirisamy M

Article GUID: 31817343
Nano-Bio Interactions of Extracellular Vesicles with Gold Nanoislands for Early Cancer Diagnosis.

Author(s): Bathini S, Raju D, Badilescu S, Kumar A, Ouellette RJ, Ghosh A, Packirisamy M

Res (Wash D C). 2018;2018:3917986 Authors: Bathini S, Raju D, Badilescu S, Kumar A, Ouellette RJ, Ghosh A, Packirisamy M

Article GUID: 31549028
Flow force augmented 3D suspended polymeric microfluidic (SPMF3 ) platform.

Author(s): Marzban M, Dargahi J, Packirisamy M

Electrophoresis. 2019 Feb;40(3):388-400 Authors: Marzban M, Dargahi J, Packirisamy M

Article GUID: 30025169
Tuning of Morphology and Stability of Gold Nanostars Through pH Adjustment.

Author(s): Kumar R, Badilescu S, Packirisamy M

J Nanosci Nanotechnol. 2019 Aug 01;19(8):4617-4622 Authors: Kumar R, Badilescu S, Packirisamy M

Article GUID: 30913757
Efficient Low Shear Flow-based Trapping of Biological Entities.

Author(s): Sohrabi Kashani A, Packirisamy M

Sci Rep. 2019 Apr 02;9(1):5511 Authors: Sohrabi Kashani A, Packirisamy M

Article GUID: 30940862
Acoustofluidic Micromixing Enabled Hybrid Integrated Colorimetric Sensing, for Rapid Point-of-Care Measurement of Salivary Potassium.

Author(s): Surendran V, Chiulli T, Manoharan S, Knisley S, Packirisamy M, Chandrasekaran A

Biosensors (Basel). 2019 May 28;9(2): Authors: Surendran V, Chiulli T, Manoharan S, Knisley S, Packirisamy M, Chandrasekaran A

Article GUID: 31141923
The effect of hydrogen nanobubbles on the morphology of gold-gelatin bionanocomposite films and their optical properties.

Author(s): Alsawafta M, Badilescu S, Truong VV, Packirisamy M

Nanotechnology. 2012 Feb 17;23(6):065305 Authors: Alsawafta M, Badilescu S, Truong VV, Packirisamy M

Article GUID: 22248640
Title:Efficient Low Shear Flow-based Trapping of Biological Entities.
Authors:Sohrabi Kashani A,  Packirisamy M
Link:https://www.ncbi.nlm.nih.gov/pubmed/30940862?dopt=Abstract
Category:Sci Rep
PMID:30940862
Dept Affiliation: ENCS
1 Optical Bio Microsystem Lab, Mechanical, Industrial, and Aerospace Engineering Department, Concordia University, Montreal, Quebec, H3G 1M8, Canada.
2 Optical Bio Microsystem Lab, Mechanical, Industrial, and Aerospace Engineering Department, Concordia University, Montreal, Quebec, H3G 1M8, Canada. mpackir@encs.concordia.ca.

Description:

Efficient Low Shear Flow-based Trapping of Biological Entities.

Sci Rep. 2019 Apr 02;9(1):5511

Authors: Sohrabi Kashani A, Packirisamy M

Abstract

Capturing cells or biological entities is an important and challenging step toward in-vitro studies of cells under a precisely controlled microscale environment. In this work, we have developed a compact and efficient microdevice for on-chip trapping of micro-sized particles. This hydrodynamics-based trapping system allows the isolation of polystyrene micro-particles with a shorter time while inducing a less hydrodynamic deformation and stress on the particles or cells both after and before trapping. A numerical simulation was carried out to design a hydrodynamic trapping mechanism and optimize the geometric and fluidic parameters affecting the trapping efficiency of the microfluidic network. By using the finite element analysis, the velocity field, pressure field, and hydrodynamic force on the micro particles were studied. Finally, a PDMS microfluidic device was fabricated to test the device's ability to trap polystyrene microspheres. Computational fluid analysis and experimental testing showed a high trapping efficiency that is more than 90%. This microdevice can be used for single cell studies including their biological, physical and chemical characterization.

PMID: 30940862 [PubMed - in process]