Keyword search (3,619 papers available)


Improving Safety of MRI in Patients with Deep Brain Stimulation Devices.

Author(s): Boutet A, Chow CT, Narang K, Elias GJB, Neudorfer C, Germann J, Ranjan M, Loh A, Martin AJ, Kucharczyk W, Steele CJ, Hancu I, Rezai AR, Lozano AM

Radiology. 2020 Jun 23;:192291 Authors: Boutet A, Chow CT, Narang K, Elias GJB, Neudorfer C, Germann J, Ranjan M, Loh A, Martin AJ, Kucharczyk W, Steele CJ, Hancu I, Rezai AR, Lozano AM

Article GUID: 32573388
Investigating microstructural variation in the human hippocampus using non-negative matrix factorization.

Author(s): Patel R, Steele CJ, Chen A, Patel S, Devenyi GA, Germann J, Tardif CL, Chakravarty MM

Neuroimage. 2019 Nov 09;:116348 Authors: Patel R, Steele CJ, Chen A, Patel S, Devenyi GA, Germann J, Tardif CL, Chakravarty MM

Article GUID: 31715254
High resolution atlas of the venous brain vasculature from 7 T quantitative susceptibility maps.

Author(s): Huck J, Wanner Y, Fan AP, Jäger AT, Grahl S, Schneider U, Villringer A, Steele CJ, Tardif CL, Bazin PL, Gauthier CJ

Brain Struct Funct. 2019 Jul 05;: Authors: Huck J, Wanner Y, Fan AP, Jäger AT, Grahl S, Schneider U, Villringer A, Steele CJ, Tardif CL, Bazin PL, Gauthier CJ

Article GUID: 31278570
Higher cardiovascular fitness level is associated with lower cerebrovascular reactivity and perfusion in healthy older adults.

Author(s): Intzandt B, Sabra D, Foster C, Desjardins-Crépeau L, Hoge RD, Steele CJ, Bherer L, Gauthier CJ

J Cereb Blood Flow Metab. 2019 Jul 25;:271678X19862873 Authors: Intzandt B, Sabra D, Foster C, Desjardins-Crépeau L, Hoge RD, Steele CJ, Bherer L, Gauthier CJ

Article GUID: 31342831
Advanced MRI techniques to improve our understanding of experience-induced neuroplasticity.

Author(s): Tardif CL, Gauthier CJ, Steele CJ, Bazin PL, Schäfer A, Schaefer A, Turner R, Villringer A

Neuroimage. 2016 05 01;131:55-72 Authors: Tardif CL, Gauthier CJ, Steele CJ, Bazin PL, Schäfer A, Schaefer A, Turner R, Villringer A

Article GUID: 26318050
Practice makes plasticity.

Author(s): Steele CJ, Zatorre RJ

Nat Neurosci. 2018 12;21(12):1645-1646 Authors: Steele CJ, Zatorre RJ

Article GUID: 30482944
Kinematic profiles suggest differential control processes involved in bilateral in-phase and anti-phase movements.

Author(s): Shih PC, Steele CJ, Nikulin V, Villringer A, Sehm B

Sci Rep. 2019 Mar 01;9(1):3273 Authors: Shih PC, Steele CJ, Nikulin V, Villringer A, Sehm B

Article GUID: 30824858
Neuroimaging Technological Advancements for Targeting in Functional Neurosurgery.

Author(s): Boutet A, Gramer R, Steele CJ, Elias GJB, Germann J, Maciel R, Kucharczyk W, Zrinzo L, Lozano AM, Fasano A

Curr Neurol Neurosci Rep. 2019 May 30;19(7):42 Authors: Boutet A, Gramer R, Steele CJ, Elias GJB, Germann J, Maciel R, Kucharczyk W, Zrinzo L, Lozano AM, Fasano A

Article GUID: 31144155
Investigation of the confounding effects of vasculature and metabolism on computational anatomy studies.

Author(s): Tardif CL, Steele CJ, Lampe L, Bazin PL, Ragert P, Villringer A, Gauthier CJ

Neuroimage. 2017 04 01;149:233-243 Authors: Tardif CL, Steele CJ, Lampe L, Bazin PL, Ragert P, Villringer A, Gauthier CJ

Article GUID: 28159689
Title:Higher cardiovascular fitness level is associated with lower cerebrovascular reactivity and perfusion in healthy older adults.
Authors:Intzandt B,  Sabra D,  Foster C,  Desjardins-Crépeau L,  Hoge RD,  Steele CJ,  Bherer L,  Gauthier CJ
Link:https://www.ncbi.nlm.nih.gov/pubmed/31342831?dopt=Abstract
DOI:10.1177/0271678X19862873
Category:J Cereb Blood Flow Metab
PMID:31342831
Dept Affiliation: PERFORM
1 INDI Department, Concordia University, Montreal, Canada.
2 PERFORM Centre, Concordia University, Montreal, Canada.
3 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, Canada.
4 Départment de Médecine, Université de Montréal, Canada.
5 Physics Department, Concordia University, Montreal, Canada.
6 Centre de Recherche de l'Institut de Cardiologie de Montréal, Montréal, Canada.
7 Department of Neurology and Neurosurgery, McGill University, Canada.
8 Department of Psychology, Concordia University, Montreal, Canada.
9 Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.

Description:

Higher cardiovascular fitness level is associated with lower cerebrovascular reactivity and perfusion in healthy older adults.

J Cereb Blood Flow Metab. 2019 Jul 25;:271678X19862873

Authors: Intzandt B, Sabra D, Foster C, Desjardins-Crépeau L, Hoge RD, Steele CJ, Bherer L, Gauthier CJ

Abstract

Aging is accompanied by vascular and structural changes in the brain, which include decreased grey matter volume (GMV), cerebral blood flow (CBF), and cerebrovascular reactivity (CVR). Enhanced fitness in aging has been related to preservation of GMV and CBF, and in some cases CVR, although there are contradictory relationships reported between CVR and fitness. To gain a better understanding of the complex interplay between fitness and GMV, CBF and CVR, the present study assessed these factors concurrently. Data from 50 participants, aged 55 to 72, were used to derive GMV, CBF, CVR and VO2peak. Results revealed that lower CVR was associated with higher VO2peak throughout large areas of the cerebral cortex. Within these regions lower fitness was associated with higher CBF and a faster hemodynamic response to hypercapnia. Overall, our results indicate that the relationships between age, fitness, cerebral health and cerebral hemodynamics are complex, likely involving changes in chemosensitivity and autoregulation in addition to changes in arterial stiffness. Future studies should collect other physiological outcomes in parallel with quantitative imaging, such as measures of chemosensitivity and autoregulation, to further understand the intricate effects of fitness on the aging brain, and how this may bias quantitative measures of cerebral health.

PMID: 31342831 [PubMed - as supplied by publisher]